SHARPER-enhanced benchtop NMR: improving SNR by removing couplings and approaching natural linewidths

Claire Dickson; George Peat; Matheus Rossetto; Meghan Eileen Halse; Dusan Uhrin

doi:10.1039/D2CC01325H

SHARPER-enhanced benchtop NMR: improving SNR by removing couplings and approaching natural linewidths

Claire Dickson, George Peat, Matheus Rossetto, Meghan Eileen Halse, Dusan Uhrin

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

We present a signal enhancement strategy for benchtop NMR that produces SNR increases on the order of 10 to 30 fold by collapsing the target resonance into an extremely narrow singlet. Importantly, the resultant signal is amenable to quantitative interpretation and therefore can be applied to analytical applications such as reaction monitoring.

Original language	English
Pages (from-to)	5534-5537
Number of pages	4
Journal	Chemical communications
Volume	58
DOIs	https://doi.org/10.1039/D2CC01325H
Publication status	Published - 5 Apr 2022

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10.1039/D2CC01325HLicence: CC BY

SHARPER-enhanced benchtop NMR: improving SNR by removing couplings and approaching natural linewidths
© The Royal Society of Chemistry 2022
Final published version, 1.87 MBLicence: CC BY

Lighting up Magnetic Resonance: SABRE optimisation powered by in situ detection
Halse, M. E. (Principal investigator)
EPSRC
9/07/18 → 30/09/20
Project: Research project (funded) › Research
EPSRC IAA 2017: Researcher Mobility: A strategic partnership to accelerate the impact of hyperpolarised benchtop NMR spectroscopy
Halse, M. E. (Principal investigator) & Duckett, S. B. (Co-investigator)
EPSRC
1/07/18 → 31/10/19
Project: Other project (funded) › Restricted grant
A paradigm shift in low-field NMR spectroscopy for industrial process monitoring, control and optimisation
Duckett, S. B. (Principal investigator) & Halse, M. E. (Co-investigator)
EPSRC
1/08/15 → 31/01/19
Project: Research project (funded) › Research

Cite this

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title = "SHARPER-enhanced benchtop NMR: improving SNR by removing couplings and approaching natural linewidths",

abstract = "We present a signal enhancement strategy for benchtop NMR that produces SNR increases on the order of 10 to 30 fold by collapsing the target resonance into an extremely narrow singlet. Importantly, the resultant signal is amenable to quantitative interpretation and therefore can be applied to analytical applications such as reaction monitoring.",

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AU - Uhrin, Dusan

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SHARPER-enhanced benchtop NMR: improving SNR by removing couplings and approaching natural linewidths

Abstract

Bibliographical note

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Projects

Lighting up Magnetic Resonance: SABRE optimisation powered by in situ detection

EPSRC IAA 2017: Researcher Mobility: A strategic partnership to accelerate the impact of hyperpolarised benchtop NMR spectroscopy

A paradigm shift in low-field NMR spectroscopy for industrial process monitoring, control and optimisation

Cite this