Short-term health and economic burden of gestational diabetes mellitus in Mexico: A modeling study

Sandra G Sosa-Rubi; Livia Dainelli; Irma Silva-Zolezzi; Patrick Detzel; Salvador Espino Y Sosa; Enrique Reyes-Muñoz; Carlos Chivardi; Eduardo Ortiz-Panozo; Ruy Lopez-Ridaura

doi:10.1016/j.diabres.2019.05.014

Short-term health and economic burden of gestational diabetes mellitus in Mexico: A modeling study

Sandra G Sosa-Rubi, Livia Dainelli, Irma Silva-Zolezzi, Patrick Detzel, Salvador Espino Y Sosa, Enrique Reyes-Muñoz, Carlos Chivardi, Eduardo Ortiz-Panozo, Ruy Lopez-Ridaura

Centre for Health Economics

Research output: Contribution to journal › Article › peer-review

Abstract

AIM: To estimate the annual burden of gestational diabetes mellitus (GDM) in Mexico.

METHODS: A model was built to conduct estimates from a healthcare system perspective, namely, the incremental costs of GDM pregnancy compared with non-GDM pregnancy from the first trimester until childbirth. The model used probabilities from the literature and surveys, and costs obtained from the Ministry of Health and national healthcare institutions. Scenario analyses were performed to estimate the GDM burden at different levels of incidence.

RESULTS: Although a non-GDM pregnancy cost on average USD 1880.6 (low risk was USD 1043.9 and high risk was USD 1673.5), a pregnancy with GDM cost USD 2934.9. Therefore, the total additional cost was USD 1576.2 per case. Given the considerable variability of the GDM incidence in Mexico, the total burden could range from USD 86.8 to USD 827.4 million per year.

CONCLUSIONS: GDM is one of the most frequent complications of pregnancy, but research has been insufficient regarding its epidemiological and economic burden in Latin America. This paper shows that the GDM economic burden in Mexico is substantial despite only accounting for short-term medical costs. Further research to assess the GDM incidence and evaluate its long-term consequences from a broader societal perspective in Mexico is recommended.

Original language	English
Pages (from-to)	114-124
Number of pages	11
Journal	Diabetes Research and Clinical Practice
Volume	153
DOIs	https://doi.org/10.1016/j.diabres.2019.05.014
Publication status	Published - Jul 2019

Bibliographical note

Keywords

Adult
Cost of Illness
Diabetes, Gestational/economics
Female
Humans
Mexico
Pregnancy

Access to Document

10.1016/j.diabres.2019.05.014

Cite this

@article{df33c6631ed24518bdfc117462e294d3,

title = "Short-term health and economic burden of gestational diabetes mellitus in Mexico: A modeling study",

abstract = "AIM: To estimate the annual burden of gestational diabetes mellitus (GDM) in Mexico.METHODS: A model was built to conduct estimates from a healthcare system perspective, namely, the incremental costs of GDM pregnancy compared with non-GDM pregnancy from the first trimester until childbirth. The model used probabilities from the literature and surveys, and costs obtained from the Ministry of Health and national healthcare institutions. Scenario analyses were performed to estimate the GDM burden at different levels of incidence.RESULTS: Although a non-GDM pregnancy cost on average USD 1880.6 (low risk was USD 1043.9 and high risk was USD 1673.5), a pregnancy with GDM cost USD 2934.9. Therefore, the total additional cost was USD 1576.2 per case. Given the considerable variability of the GDM incidence in Mexico, the total burden could range from USD 86.8 to USD 827.4 million per year.CONCLUSIONS: GDM is one of the most frequent complications of pregnancy, but research has been insufficient regarding its epidemiological and economic burden in Latin America. This paper shows that the GDM economic burden in Mexico is substantial despite only accounting for short-term medical costs. Further research to assess the GDM incidence and evaluate its long-term consequences from a broader societal perspective in Mexico is recommended.",

keywords = "Adult, Cost of Illness, Diabetes, Gestational/economics, Female, Humans, Mexico, Pregnancy",

author = "Sosa-Rubi, {Sandra G} and Livia Dainelli and Irma Silva-Zolezzi and Patrick Detzel and {Espino Y Sosa}, Salvador and Enrique Reyes-Mu{\~n}oz and Carlos Chivardi and Eduardo Ortiz-Panozo and Ruy Lopez-Ridaura",

note = "Copyright {\textcopyright} 2019. Published by Elsevier B.V.",

year = "2019",

month = jul,

doi = "10.1016/j.diabres.2019.05.014",

language = "English",

volume = "153",

pages = "114--124",

journal = "Diabetes Research and Clinical Practice",

issn = "0168-8227",

publisher = "Elsevier",

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TY - JOUR

T1 - Short-term health and economic burden of gestational diabetes mellitus in Mexico

T2 - A modeling study

AU - Sosa-Rubi, Sandra G

AU - Dainelli, Livia

AU - Silva-Zolezzi, Irma

AU - Detzel, Patrick

AU - Espino Y Sosa, Salvador

AU - Reyes-Muñoz, Enrique

AU - Chivardi, Carlos

AU - Ortiz-Panozo, Eduardo

AU - Lopez-Ridaura, Ruy

PY - 2019/7

Y1 - 2019/7

N2 - AIM: To estimate the annual burden of gestational diabetes mellitus (GDM) in Mexico.METHODS: A model was built to conduct estimates from a healthcare system perspective, namely, the incremental costs of GDM pregnancy compared with non-GDM pregnancy from the first trimester until childbirth. The model used probabilities from the literature and surveys, and costs obtained from the Ministry of Health and national healthcare institutions. Scenario analyses were performed to estimate the GDM burden at different levels of incidence.RESULTS: Although a non-GDM pregnancy cost on average USD 1880.6 (low risk was USD 1043.9 and high risk was USD 1673.5), a pregnancy with GDM cost USD 2934.9. Therefore, the total additional cost was USD 1576.2 per case. Given the considerable variability of the GDM incidence in Mexico, the total burden could range from USD 86.8 to USD 827.4 million per year.CONCLUSIONS: GDM is one of the most frequent complications of pregnancy, but research has been insufficient regarding its epidemiological and economic burden in Latin America. This paper shows that the GDM economic burden in Mexico is substantial despite only accounting for short-term medical costs. Further research to assess the GDM incidence and evaluate its long-term consequences from a broader societal perspective in Mexico is recommended.

AB - AIM: To estimate the annual burden of gestational diabetes mellitus (GDM) in Mexico.METHODS: A model was built to conduct estimates from a healthcare system perspective, namely, the incremental costs of GDM pregnancy compared with non-GDM pregnancy from the first trimester until childbirth. The model used probabilities from the literature and surveys, and costs obtained from the Ministry of Health and national healthcare institutions. Scenario analyses were performed to estimate the GDM burden at different levels of incidence.RESULTS: Although a non-GDM pregnancy cost on average USD 1880.6 (low risk was USD 1043.9 and high risk was USD 1673.5), a pregnancy with GDM cost USD 2934.9. Therefore, the total additional cost was USD 1576.2 per case. Given the considerable variability of the GDM incidence in Mexico, the total burden could range from USD 86.8 to USD 827.4 million per year.CONCLUSIONS: GDM is one of the most frequent complications of pregnancy, but research has been insufficient regarding its epidemiological and economic burden in Latin America. This paper shows that the GDM economic burden in Mexico is substantial despite only accounting for short-term medical costs. Further research to assess the GDM incidence and evaluate its long-term consequences from a broader societal perspective in Mexico is recommended.

KW - Adult

KW - Cost of Illness

KW - Diabetes, Gestational/economics

KW - Female

KW - Humans

KW - Mexico

KW - Pregnancy

U2 - 10.1016/j.diabres.2019.05.014

DO - 10.1016/j.diabres.2019.05.014

M3 - Article

C2 - 31108135

SN - 0168-8227

VL - 153

SP - 114

EP - 124

JO - Diabetes Research and Clinical Practice

JF - Diabetes Research and Clinical Practice

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