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Simulation Modelling in Ophthalmology: Application to Cost Effectiveness of Ranibizumab and Aflibercept for the Treatment of Wet Age-Related Macular Degeneration in the United Kingdom

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JournalPharmacoEconomics
DateE-pub ahead of print - 27 Oct 2016
DatePublished (current) - Oct 2016
Number of pages13
Pages (from-to)1-12
Early online date27/10/16
Original languageEnglish

Abstract

Previously developed models in ophthalmology have generally used a Markovian structure. There are a number of limitations with this approach, most notably the ability to base patient outcomes on best-corrected visual acuity (BCVA) in both eyes, which may be overcome using a different modelling structure. Simulation modelling allows for this to be modelled more precisely, and therefore may provide more accurate and relevant estimates of the cost effectiveness of ophthalmology interventions.

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