Single-cell analyses reveal aberrant pathways for megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets

Bethan  Psaila; Guanlin Wang; Alba  Rodriguez Meira; Rong  Li; Elisabeth F.  Heuston; Lauren  Murphy; Daniel Yee; Ian Stuart Hitchcock; Nikolaos  Sousos; Jennifer  O'Sullivan; Stacie  Anderson; Yotis A.  Senis; Olga K.  Weinberg; Monica L.  Calicchio; Deena  Iskander; Daniel  Royston; Dragana  Milojkovic; Irene  Roberts; David M.  Bodine; Supat  Thongjuea; Adam J. Mead

doi:10.1016/j.molcel.2020.04.008

Single-cell analyses reveal aberrant pathways for megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets

Bethan Psaila, Guanlin Wang, Alba Rodriguez Meira, Rong Li, Elisabeth F. Heuston, Lauren Murphy, Daniel Yee, Ian Stuart Hitchcock, Nikolaos Sousos, Jennifer O'Sullivan, Stacie Anderson, Yotis A. Senis, Olga K. Weinberg, Monica L. Calicchio, Deena Iskander, Daniel Royston, Dragana Milojkovic, Irene Roberts, David M. Bodine, Supat ThongjueaAdam J. Mead

Biology

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	477-492.e8
Number of pages	25
Journal	Molecular Cell
Volume	78
Issue number	3
DOIs	https://doi.org/10.1016/j.molcel.2020.04.008
Publication status	Published - 7 May 2020

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10.1016/j.molcel.2020.04.008

Single-Cell Analyses Reveal Megakaryocyte-BiasedHematopoiesis in Myelofibrosis and IdentifyMutant Clone-Specific Targets
© 2020 The Authors.
Final published version, 6.92 MBLicence: CC BY

Cite this

Psaila, B., Wang, G., Rodriguez Meira, A., Li, R., Heuston, E. F., Murphy, L., Yee, D., Hitchcock, I. S., Sousos, N., O'Sullivan, J., Anderson, S., Senis, Y. A., Weinberg, O. K., Calicchio, M. L., Iskander, D., Royston, D., Milojkovic, D., Roberts, I., Bodine, D. M., ... Mead, A. J. (2020). Single-cell analyses reveal aberrant pathways for megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets. Molecular Cell, 78(3), 477-492.e8. https://doi.org/10.1016/j.molcel.2020.04.008

@article{b6810811bc844890876572a3a59630aa,

title = "Single-cell analyses reveal aberrant pathways for megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets",

author = "Bethan Psaila and Guanlin Wang and {Rodriguez Meira}, Alba and Rong Li and Heuston, {Elisabeth F.} and Lauren Murphy and Daniel Yee and Hitchcock, {Ian Stuart} and Nikolaos Sousos and Jennifer O'Sullivan and Stacie Anderson and Senis, {Yotis A.} and Weinberg, {Olga K.} and Calicchio, {Monica L.} and Deena Iskander and Daniel Royston and Dragana Milojkovic and Irene Roberts and Bodine, {David M.} and Supat Thongjuea and Mead, {Adam J.}",

note = "{\textcopyright} 2020 The Authors.",

year = "2020",

month = may,

day = "7",

doi = "10.1016/j.molcel.2020.04.008",

language = "English",

volume = "78",

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Psaila, B, Wang, G, Rodriguez Meira, A, Li, R, Heuston, EF, Murphy, L, Yee, D , Hitchcock, IS, Sousos, N, O'Sullivan, J, Anderson, S, Senis, YA, Weinberg, OK, Calicchio, ML, Iskander, D, Royston, D, Milojkovic, D, Roberts, I, Bodine, DM, Thongjuea, S & Mead, AJ 2020, 'Single-cell analyses reveal aberrant pathways for megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets', Molecular Cell, vol. 78, no. 3, pp. 477-492.e8. https://doi.org/10.1016/j.molcel.2020.04.008

TY - JOUR

T1 - Single-cell analyses reveal aberrant pathways for megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets

AU - Psaila, Bethan

AU - Wang, Guanlin

AU - Rodriguez Meira, Alba

AU - Li, Rong

AU - Heuston, Elisabeth F.

AU - Murphy, Lauren

AU - Yee, Daniel

AU - Hitchcock, Ian Stuart

AU - Sousos, Nikolaos

AU - O'Sullivan, Jennifer

AU - Anderson, Stacie

AU - Senis, Yotis A.

AU - Weinberg, Olga K.

AU - Calicchio, Monica L.

AU - Iskander, Deena

AU - Royston, Daniel

AU - Milojkovic, Dragana

AU - Roberts, Irene

AU - Bodine, David M.

AU - Thongjuea, Supat

AU - Mead, Adam J.

PY - 2020/5/7

Y1 - 2020/5/7

U2 - 10.1016/j.molcel.2020.04.008

DO - 10.1016/j.molcel.2020.04.008

M3 - Article

SN - 1097-2765

VL - 78

SP - 477-492.e8

JO - Molecular Cell

JF - Molecular Cell

IS - 3

ER -