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Site-specific deamidation of glutamine: a new marker of bone collagen deterioration

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JournalRapid communications in mass spectrometry
DatePublished - 15 Oct 2012
Issue number19
Volume26
Number of pages9
Pages (from-to)2319-27
Original languageEnglish

Abstract

Non-enzymatic deamidation accumulates in aging tissues in vivo and has been proposed to be potentially useful as a molecular clock. The process continues post mortem, and here we explore the increase in levels of deamidation in archaeological collagen, as measured during Zooarchaeology by Mass Spectrometry (ZooMS) analysis.

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