Sleep Deprivation Induces Fragmented Memory Loss

TY - JOUR

T1 - Sleep Deprivation Induces Fragmented Memory Loss

AU - Ashton, Jennifer

AU - Harrington, Marcus Oliver

AU - Langthorne, Diane

AU - Ngo, Hong-Viet

AU - Cairney, Scott Ashley

N1 - This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

PY - 2020/3

Y1 - 2020/3

N2 - Sleep deprivation increases rates of forgetting in episodic memory. Yet, whether an extended lack of sleep alters the qualitative nature of forgetting is unknown. We compared forgetting of episodic memories across intervals of overnight sleep, daytime wakefulness and overnight sleep deprivation. Item-level forgetting was amplified across daytime wakefulness and overnight sleep deprivation, as compared to sleep. Importantly, however, overnight sleep deprivation led to a further deficit in associative memory that was not observed after daytime wakefulness. These findings suggest that sleep deprivation induces fragmentation among item memories and their associations, altering the qualitative nature of episodic forgetting.

AB - Sleep deprivation increases rates of forgetting in episodic memory. Yet, whether an extended lack of sleep alters the qualitative nature of forgetting is unknown. We compared forgetting of episodic memories across intervals of overnight sleep, daytime wakefulness and overnight sleep deprivation. Item-level forgetting was amplified across daytime wakefulness and overnight sleep deprivation, as compared to sleep. Importantly, however, overnight sleep deprivation led to a further deficit in associative memory that was not observed after daytime wakefulness. These findings suggest that sleep deprivation induces fragmentation among item memories and their associations, altering the qualitative nature of episodic forgetting.

U2 - 10.1101/lm.050757.119

DO - 10.1101/lm.050757.119

M3 - Article

SN - 1072-0502

VL - 31

SP - 130

EP - 135

JO - Learning & memory (Cold Spring Harbor, N.Y.)

JF - Learning & memory (Cold Spring Harbor, N.Y.)

IS - 3

ER -