Solvent effects on supramolecular gel-phase materials: Two-component dendritic gel

A R  Hirst; D K  Smith

doi:10.1021/la048178c

Solvent effects on supramolecular gel-phase materials: Two-component dendritic gel

A R Hirst, D K Smith

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The self-assembly of diaminododecane with dendritic L-lysine-based peptides to form gel-phase materials was investigated in a range of different solvents. The degree of structuring was modulated by the solvent employed, an effect which induced subtle changes in the mesoscale aggregate morphology and macroscopic behavior of the self-assembled state. In this paper a range of different solvent parameters are investigated, and it is clearly shown that macroscopic gelation can be related to a solvent polar solubility parameter for this system. The results also show a dependence on Kamlet-Taft hydrogen bonding parameters, and this clearly demonstrates the role of the solvent environment in terms of dendron-dendron intermolecular hydrogen bonding and its impact on the supramolecular chiral organization of the assembled superstructure.

Original language	English
Pages (from-to)	10851-10857
Number of pages	7
Journal	Langmuir
Volume	20
Issue number	25
DOIs	https://doi.org/10.1021/la048178c
Publication status	Published - 7 Dec 2004

Keywords

2-DIRECTIONAL CASCADE MOLECULES
ONE-COMPONENT
ASSOCIATION PROPERTIES
SOLUBILITY PARAMETERS
PEPTIDIC DENDRIMERS
ORGANIC-SOLVENTS
AQUEOUS-SOLUTION
SELF-ASSEMBLIES
WEIGHT GELATORS
ETHYLENE-OXIDE

Access to Document

10.1021/la048178c

Cite this

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title = "Solvent effects on supramolecular gel-phase materials: Two-component dendritic gel",

abstract = "The self-assembly of diaminododecane with dendritic L-lysine-based peptides to form gel-phase materials was investigated in a range of different solvents. The degree of structuring was modulated by the solvent employed, an effect which induced subtle changes in the mesoscale aggregate morphology and macroscopic behavior of the self-assembled state. In this paper a range of different solvent parameters are investigated, and it is clearly shown that macroscopic gelation can be related to a solvent polar solubility parameter for this system. The results also show a dependence on Kamlet-Taft hydrogen bonding parameters, and this clearly demonstrates the role of the solvent environment in terms of dendron-dendron intermolecular hydrogen bonding and its impact on the supramolecular chiral organization of the assembled superstructure.",

keywords = "2-DIRECTIONAL CASCADE MOLECULES, ONE-COMPONENT, ASSOCIATION PROPERTIES, SOLUBILITY PARAMETERS, PEPTIDIC DENDRIMERS, ORGANIC-SOLVENTS, AQUEOUS-SOLUTION, SELF-ASSEMBLIES, WEIGHT GELATORS, ETHYLENE-OXIDE",

author = "Hirst, {A R} and Smith, {D K}",

year = "2004",

month = dec,

day = "7",

doi = "10.1021/la048178c",

language = "English",

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journal = "Langmuir",

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publisher = "American Chemical Society",

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TY - JOUR

T1 - Solvent effects on supramolecular gel-phase materials: Two-component dendritic gel

AU - Hirst, A R

AU - Smith, D K

PY - 2004/12/7

Y1 - 2004/12/7

N2 - The self-assembly of diaminododecane with dendritic L-lysine-based peptides to form gel-phase materials was investigated in a range of different solvents. The degree of structuring was modulated by the solvent employed, an effect which induced subtle changes in the mesoscale aggregate morphology and macroscopic behavior of the self-assembled state. In this paper a range of different solvent parameters are investigated, and it is clearly shown that macroscopic gelation can be related to a solvent polar solubility parameter for this system. The results also show a dependence on Kamlet-Taft hydrogen bonding parameters, and this clearly demonstrates the role of the solvent environment in terms of dendron-dendron intermolecular hydrogen bonding and its impact on the supramolecular chiral organization of the assembled superstructure.

AB - The self-assembly of diaminododecane with dendritic L-lysine-based peptides to form gel-phase materials was investigated in a range of different solvents. The degree of structuring was modulated by the solvent employed, an effect which induced subtle changes in the mesoscale aggregate morphology and macroscopic behavior of the self-assembled state. In this paper a range of different solvent parameters are investigated, and it is clearly shown that macroscopic gelation can be related to a solvent polar solubility parameter for this system. The results also show a dependence on Kamlet-Taft hydrogen bonding parameters, and this clearly demonstrates the role of the solvent environment in terms of dendron-dendron intermolecular hydrogen bonding and its impact on the supramolecular chiral organization of the assembled superstructure.

KW - 2-DIRECTIONAL CASCADE MOLECULES

KW - ONE-COMPONENT

KW - ASSOCIATION PROPERTIES

KW - SOLUBILITY PARAMETERS

KW - PEPTIDIC DENDRIMERS

KW - ORGANIC-SOLVENTS

KW - AQUEOUS-SOLUTION

KW - SELF-ASSEMBLIES

KW - WEIGHT GELATORS

KW - ETHYLENE-OXIDE

U2 - 10.1021/la048178c

DO - 10.1021/la048178c

M3 - Article

SN - 0743-7463

VL - 20

SP - 10851

EP - 10857

JO - Langmuir

JF - Langmuir

IS - 25

ER -