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Standardising the Unknown: practicable pluripotency as doable futures

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Standardising the Unknown : practicable pluripotency as doable futures. / Webster, Andrew Joseph; Eriksson, Lena.

In: Science as Culture, Vol. 17, No. 1, 2008, p. 57-69.

Research output: Contribution to journalArticlepeer-review

Harvard

Webster, AJ & Eriksson, L 2008, 'Standardising the Unknown: practicable pluripotency as doable futures', Science as Culture, vol. 17, no. 1, pp. 57-69. https://doi.org/10.1080/09505430701872814

APA

Webster, A. J., & Eriksson, L. (2008). Standardising the Unknown: practicable pluripotency as doable futures. Science as Culture, 17(1), 57-69. https://doi.org/10.1080/09505430701872814

Vancouver

Webster AJ, Eriksson L. Standardising the Unknown: practicable pluripotency as doable futures. Science as Culture. 2008;17(1):57-69. https://doi.org/10.1080/09505430701872814

Author

Webster, Andrew Joseph ; Eriksson, Lena. / Standardising the Unknown : practicable pluripotency as doable futures. In: Science as Culture. 2008 ; Vol. 17, No. 1. pp. 57-69.

Bibtex - Download

@article{5576b17d5c9a420692df1bbe51da37d0,
title = "Standardising the Unknown: practicable pluripotency as doable futures",
abstract = "To standardize human embryonic stem cells is an exercise in standardizing different kinds of unknowns. Such standards, currently being developed in the field, can change the understanding of what a stem cell is. In the influential International Stem Cell Initiative (ISCI), scientists in a fiercely competitive field are prepared to exchange research material and data that would normally be highly confidential. ISCI participants understand the particular unknown that they are seeking to standardize as a {\textquoteleft}known unknown{\textquoteright} and hope that their collaborative work will serve to move the field forward and thus enable both competition and comparable data. Such known unknowns are seen to be of vital importance, yet of a different epistemic currency than the types of unknowns that could lead to scientific fame and fortune. Furthermore, while the notion of {\textquoteleft}pluripotency{\textquoteright} is of pivotal importance as a discursive resource when demarcating the abilities of embryonic stem cells from those of adult stem cells, it can also present a practical problem. A more flexible definition allowing for different stem cell {\textquoteleft}niches{\textquoteright} could render the cell lines less pluri but more potent. The reconfiguration of pluripotency may serve to transport human embryonic stem cells into a clinical and {\textquoteleft}doable{\textquoteright} future.",
author = "Webster, {Andrew Joseph} and Lena Eriksson",
year = "2008",
doi = "10.1080/09505430701872814",
language = "English",
volume = "17",
pages = "57--69",
journal = "Science as Culture",
issn = "0950-5431",
publisher = "Routledge",
number = "1",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Standardising the Unknown

T2 - practicable pluripotency as doable futures

AU - Webster, Andrew Joseph

AU - Eriksson, Lena

PY - 2008

Y1 - 2008

N2 - To standardize human embryonic stem cells is an exercise in standardizing different kinds of unknowns. Such standards, currently being developed in the field, can change the understanding of what a stem cell is. In the influential International Stem Cell Initiative (ISCI), scientists in a fiercely competitive field are prepared to exchange research material and data that would normally be highly confidential. ISCI participants understand the particular unknown that they are seeking to standardize as a ‘known unknown’ and hope that their collaborative work will serve to move the field forward and thus enable both competition and comparable data. Such known unknowns are seen to be of vital importance, yet of a different epistemic currency than the types of unknowns that could lead to scientific fame and fortune. Furthermore, while the notion of ‘pluripotency’ is of pivotal importance as a discursive resource when demarcating the abilities of embryonic stem cells from those of adult stem cells, it can also present a practical problem. A more flexible definition allowing for different stem cell ‘niches’ could render the cell lines less pluri but more potent. The reconfiguration of pluripotency may serve to transport human embryonic stem cells into a clinical and ‘doable’ future.

AB - To standardize human embryonic stem cells is an exercise in standardizing different kinds of unknowns. Such standards, currently being developed in the field, can change the understanding of what a stem cell is. In the influential International Stem Cell Initiative (ISCI), scientists in a fiercely competitive field are prepared to exchange research material and data that would normally be highly confidential. ISCI participants understand the particular unknown that they are seeking to standardize as a ‘known unknown’ and hope that their collaborative work will serve to move the field forward and thus enable both competition and comparable data. Such known unknowns are seen to be of vital importance, yet of a different epistemic currency than the types of unknowns that could lead to scientific fame and fortune. Furthermore, while the notion of ‘pluripotency’ is of pivotal importance as a discursive resource when demarcating the abilities of embryonic stem cells from those of adult stem cells, it can also present a practical problem. A more flexible definition allowing for different stem cell ‘niches’ could render the cell lines less pluri but more potent. The reconfiguration of pluripotency may serve to transport human embryonic stem cells into a clinical and ‘doable’ future.

U2 - 10.1080/09505430701872814

DO - 10.1080/09505430701872814

M3 - Article

VL - 17

SP - 57

EP - 69

JO - Science as Culture

JF - Science as Culture

SN - 0950-5431

IS - 1

ER -