Stress induces peroxisome biogenesis genes

E Lopez-Huertas; W L Charlton; B Johnson; I A Graham; A Baker

Stress induces peroxisome biogenesis genes

E Lopez-Huertas, W L Charlton, B Johnson, I A Graham, A Baker

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Research output: Contribution to journal › Article › peer-review

Abstract

Peroxisomes are the cellular location of many antioxidants and are themselves significant producers of reactive oxygen species. In this report we demonstrate the induction of peroxisome biogenesis genes in both plant and animal cells by the universal stress signal molecule hydrogen peroxide, Using PEX1-LUC transgenic plants, rapid local and systemic induction of PEX1-luciferase could be demonstrated in vivo in response to physiological levels of hydrogen peroxide, PEX1-luciferase was also induced in response to wounding and to infection with an avirulent pathogen. We propose a model in which various stress situations that lead to the production of hydrogen peroxide can be ameliorated by elaboration of the peroxisome compartment to assist in restoration of the cellular redox balance.

Original language	English
Pages (from-to)	6770-6777
Number of pages	8
Journal	EMBO Journal
Volume	19
Issue number	24
Publication status	Published - 15 Dec 2000

Keywords

hydrogen peroxide
oxidative stress
PEX genes
plant pathogenesis
wounding
NICOTIANA-PLUMBAGINIFOLIA L
FUNCTIONAL COMPLEMENTATION
DISEASE RESISTANCE
PTS1 RECEPTOR
CDNA CLONING
CELL MUTANT
PROLIFERATION
PLANTS
ARABIDOPSIS
SENESCENCE

Cite this

@article{1539a9d0604d487aa8c0519c2326ce24,

title = "Stress induces peroxisome biogenesis genes",

abstract = "Peroxisomes are the cellular location of many antioxidants and are themselves significant producers of reactive oxygen species. In this report we demonstrate the induction of peroxisome biogenesis genes in both plant and animal cells by the universal stress signal molecule hydrogen peroxide, Using PEX1-LUC transgenic plants, rapid local and systemic induction of PEX1-luciferase could be demonstrated in vivo in response to physiological levels of hydrogen peroxide, PEX1-luciferase was also induced in response to wounding and to infection with an avirulent pathogen. We propose a model in which various stress situations that lead to the production of hydrogen peroxide can be ameliorated by elaboration of the peroxisome compartment to assist in restoration of the cellular redox balance.",

keywords = "hydrogen peroxide, oxidative stress, PEX genes, plant pathogenesis, wounding, NICOTIANA-PLUMBAGINIFOLIA L, FUNCTIONAL COMPLEMENTATION, DISEASE RESISTANCE, PTS1 RECEPTOR, CDNA CLONING, CELL MUTANT, PROLIFERATION, PLANTS, ARABIDOPSIS, SENESCENCE",

author = "E Lopez-Huertas and Charlton, {W L} and B Johnson and Graham, {I A} and A Baker",

year = "2000",

month = dec,

day = "15",

language = "English",

volume = "19",

pages = "6770--6777",

journal = "EMBO Journal",

issn = "0261-4189",

publisher = "Springer",

number = "24",

}

TY - JOUR

T1 - Stress induces peroxisome biogenesis genes

AU - Lopez-Huertas, E

AU - Charlton, W L

AU - Johnson, B

AU - Graham, I A

AU - Baker, A

PY - 2000/12/15

Y1 - 2000/12/15

N2 - Peroxisomes are the cellular location of many antioxidants and are themselves significant producers of reactive oxygen species. In this report we demonstrate the induction of peroxisome biogenesis genes in both plant and animal cells by the universal stress signal molecule hydrogen peroxide, Using PEX1-LUC transgenic plants, rapid local and systemic induction of PEX1-luciferase could be demonstrated in vivo in response to physiological levels of hydrogen peroxide, PEX1-luciferase was also induced in response to wounding and to infection with an avirulent pathogen. We propose a model in which various stress situations that lead to the production of hydrogen peroxide can be ameliorated by elaboration of the peroxisome compartment to assist in restoration of the cellular redox balance.

AB - Peroxisomes are the cellular location of many antioxidants and are themselves significant producers of reactive oxygen species. In this report we demonstrate the induction of peroxisome biogenesis genes in both plant and animal cells by the universal stress signal molecule hydrogen peroxide, Using PEX1-LUC transgenic plants, rapid local and systemic induction of PEX1-luciferase could be demonstrated in vivo in response to physiological levels of hydrogen peroxide, PEX1-luciferase was also induced in response to wounding and to infection with an avirulent pathogen. We propose a model in which various stress situations that lead to the production of hydrogen peroxide can be ameliorated by elaboration of the peroxisome compartment to assist in restoration of the cellular redox balance.

KW - hydrogen peroxide

KW - oxidative stress

KW - PEX genes

KW - plant pathogenesis

KW - wounding

KW - NICOTIANA-PLUMBAGINIFOLIA L

KW - FUNCTIONAL COMPLEMENTATION

KW - DISEASE RESISTANCE

KW - PTS1 RECEPTOR

KW - CDNA CLONING

KW - CELL MUTANT

KW - PROLIFERATION

KW - PLANTS

KW - ARABIDOPSIS

KW - SENESCENCE

M3 - Article

SN - 0261-4189

VL - 19

SP - 6770

EP - 6777

JO - EMBO Journal

JF - EMBO Journal

IS - 24

ER -