Structures of the Apo and FAD-Bound Forms of 2-Hydroxybiphenyl 3-monooxygenase (HbpA) Locate Activity Hotspots Identified by Using Directed Evolution

Chantel N. Jensen, Tamara Mielke, Joseph E. Farrugia, Annika Frank, Henry Man, Sam Hart, Johan P. Turkenburg, Gideon Grogan

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)968–976
Number of pages9
JournalChembiochem
Volume16
Issue number6
DOIs
Publication statusPublished - 13 Apr 2015

Bibliographical note

© 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Keywords

  • biotransformations, FAD, flavoprotein, hydroxylation, monooxygenases

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