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Substrate scope in the direct imine acylation of ortho-substituted benzoic acid derivatives: the total synthesis (±)-cavidine

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Substrate scope in the direct imine acylation of ortho-substituted benzoic acid derivatives : the total synthesis (±)-cavidine. / Kitsiou, Christiana; Unsworth, William P.; Coulthard, Graeme; Taylor, Richard J K.

In: Tetrahedron, Vol. 70, No. 40, 07.10.2014, p. 7172-7180.

Research output: Contribution to journalArticle

Harvard

Kitsiou, C, Unsworth, WP, Coulthard, G & Taylor, RJK 2014, 'Substrate scope in the direct imine acylation of ortho-substituted benzoic acid derivatives: the total synthesis (±)-cavidine', Tetrahedron, vol. 70, no. 40, pp. 7172-7180. https://doi.org/10.1016/j.tet.2014.04.066

APA

Kitsiou, C., Unsworth, W. P., Coulthard, G., & Taylor, R. J. K. (2014). Substrate scope in the direct imine acylation of ortho-substituted benzoic acid derivatives: the total synthesis (±)-cavidine. Tetrahedron, 70(40), 7172-7180. https://doi.org/10.1016/j.tet.2014.04.066

Vancouver

Kitsiou C, Unsworth WP, Coulthard G, Taylor RJK. Substrate scope in the direct imine acylation of ortho-substituted benzoic acid derivatives: the total synthesis (±)-cavidine. Tetrahedron. 2014 Oct 7;70(40):7172-7180. https://doi.org/10.1016/j.tet.2014.04.066

Author

Kitsiou, Christiana ; Unsworth, William P. ; Coulthard, Graeme ; Taylor, Richard J K. / Substrate scope in the direct imine acylation of ortho-substituted benzoic acid derivatives : the total synthesis (±)-cavidine. In: Tetrahedron. 2014 ; Vol. 70, No. 40. pp. 7172-7180.

Bibtex - Download

@article{fa1de539f1224666bc57eeec8efe2b8c,
title = "Substrate scope in the direct imine acylation of ortho-substituted benzoic acid derivatives: the total synthesis (±)-cavidine",
abstract = "The direct imine acylation (DIA) and subsequent cyclisation of a range of imines with ortho-substituted benzoic acid derivatives is described. Variation in the coupling reagents, imine and benzoic acid were all examined. The DIA procedure was also applied in the total synthesis of (±)-cavidine.",
keywords = "Cavidine, Evodiamine, Molecular diversity, N-Acyliminium ions, Nitrogen heterocycles",
author = "Christiana Kitsiou and Unsworth, {William P.} and Graeme Coulthard and Taylor, {Richard J K}",
year = "2014",
month = "10",
day = "7",
doi = "10.1016/j.tet.2014.04.066",
language = "English",
volume = "70",
pages = "7172--7180",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",
number = "40",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - Substrate scope in the direct imine acylation of ortho-substituted benzoic acid derivatives

T2 - the total synthesis (±)-cavidine

AU - Kitsiou, Christiana

AU - Unsworth, William P.

AU - Coulthard, Graeme

AU - Taylor, Richard J K

PY - 2014/10/7

Y1 - 2014/10/7

N2 - The direct imine acylation (DIA) and subsequent cyclisation of a range of imines with ortho-substituted benzoic acid derivatives is described. Variation in the coupling reagents, imine and benzoic acid were all examined. The DIA procedure was also applied in the total synthesis of (±)-cavidine.

AB - The direct imine acylation (DIA) and subsequent cyclisation of a range of imines with ortho-substituted benzoic acid derivatives is described. Variation in the coupling reagents, imine and benzoic acid were all examined. The DIA procedure was also applied in the total synthesis of (±)-cavidine.

KW - Cavidine

KW - Evodiamine

KW - Molecular diversity

KW - N-Acyliminium ions

KW - Nitrogen heterocycles

UR - http://www.scopus.com/inward/record.url?scp=84902039785&partnerID=8YFLogxK

U2 - 10.1016/j.tet.2014.04.066

DO - 10.1016/j.tet.2014.04.066

M3 - Article

VL - 70

SP - 7172

EP - 7180

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

IS - 40

ER -