By the same authors

From the same journal

Surprises and pitfalls arising from (pseudo)symmetry

Research output: Contribution to journalArticle

Published copy (DOI)

Author(s)

Department/unit(s)

Publication details

JournalActa crystallographica section d-Biological crystallography
DatePublished - 4 Jan 2008
Issue number1
Volume64
Number of pages9
Pages (from-to)99-107
Original languageEnglish

Abstract

It is not uncommon for protein crystals to crystallize with more than a single molecule per asymmetric unit. When more than a single molecule is present in the asymmetric unit, various pathological situations such as twinning, modulated crystals and pseudo translational or rotational symmetry can arise. The presence of pseudosymmetry can lead to uncertainties about the correct space group, especially in the presence of twinning. The background to certain common pathologies is presented and a new notation for space groups in unusual settings is introduced. The main concepts are illustrated with several examples from the literature and the Protein Data Bank.

    Research areas

  • CRYSTALLOGRAPHIC STRUCTURE DETERMINATION, ORTHORHOMBIC DIFFRACTION PATTERNS, PROTEIN CRYSTAL-STRUCTURE, ELECTRON-DENSITY MAPS, MOLECULAR REPLACEMENT, TWINNED CRYSTALS, OD-STRUCTURES, OROTIDINE-5'-MONOPHOSPHATE DECARBOXYLASE, MACROMOLECULAR STRUCTURES, STRUCTURAL BASIS

Discover related content

Find related publications, people, projects, datasets and more using interactive charts.

View graph of relations