SYNTHESIS OF BROMOXONE

E C L  GAUTIER; N J  LEWIS; A  MCKILLOP; R J K  TAYLOR

SYNTHESIS OF BROMOXONE

E C L GAUTIER, N J LEWIS, A MCKILLOP, R J K TAYLOR

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A short synthetic route to the natural product bromoxone is reported (5 steps, 15% overall yield), involving regioselective monoepoxidation of an electrolytically-derived quinone monoketal followed by stereoselective ketone reduction.

Original language	English
Pages (from-to)	8759-8760
Number of pages	2
Journal	Tetrahedron Letters
Volume	35
Issue number	47
Publication status	Published - 21 Nov 1994

Keywords

QUINONE BISKETALS
STREPTOMYCES
ARANOROSIN
ROUTE

Cite this

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title = "SYNTHESIS OF BROMOXONE",

abstract = "A short synthetic route to the natural product bromoxone is reported (5 steps, 15% overall yield), involving regioselective monoepoxidation of an electrolytically-derived quinone monoketal followed by stereoselective ketone reduction.",

keywords = "QUINONE BISKETALS, STREPTOMYCES, ARANOROSIN, ROUTE",

author = "GAUTIER, {E C L} and LEWIS, {N J} and A MCKILLOP and TAYLOR, {R J K}",

year = "1994",

month = nov,

day = "21",

language = "English",

volume = "35",

pages = "8759--8760",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "47",

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TY - JOUR

T1 - SYNTHESIS OF BROMOXONE

AU - GAUTIER, E C L

AU - LEWIS, N J

AU - MCKILLOP, A

AU - TAYLOR, R J K

PY - 1994/11/21

Y1 - 1994/11/21

N2 - A short synthetic route to the natural product bromoxone is reported (5 steps, 15% overall yield), involving regioselective monoepoxidation of an electrolytically-derived quinone monoketal followed by stereoselective ketone reduction.

AB - A short synthetic route to the natural product bromoxone is reported (5 steps, 15% overall yield), involving regioselective monoepoxidation of an electrolytically-derived quinone monoketal followed by stereoselective ketone reduction.

KW - QUINONE BISKETALS

KW - STREPTOMYCES

KW - ARANOROSIN

KW - ROUTE

M3 - Article

SN - 0040-4039

VL - 35

SP - 8759

EP - 8760

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 47

ER -