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Synthetic Approaches for Accessing Pseudaminic Acid (Pse) Bacterial Glycans

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JournalChembiochem
DateAccepted/In press - 15 Jan 2020
DateE-pub ahead of print (current) - 26 Feb 2020
Volume21
Pages (from-to)1-12
Early online date26/02/20
Original languageEnglish

Abstract

Sugars to order: A summary of work in the field of pseudaminic acid (Pse) synthesis is provided. This non‐mammalian sugar is of increasing biological importance as an essential component in cell‐surface glycoconjugates of a number of pathogenic bacteria. Pioneering studies into biosynthesis of Pse5Ac7Ac have provided inspiration to carbohydrate chemists.

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