SYNTHETIC STUDIES TOWARDS ARANOROSIN

A  MCKILLOP; L  MCLAREN; R J K  TAYLOR; R J  WATSON; N  LEWIS

SYNTHETIC STUDIES TOWARDS ARANOROSIN

A MCKILLOP, L MCLAREN, R J K TAYLOR, R J WATSON, N LEWIS

Chemistry

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Hypervalent iodine reagents have been employed for the conversion of tyrosine derivatives 4a-d, 5 into 3-substituted 1-oxaspiro[4,5]deca-6,9-diene-2,8-diones 3a-d, 6, which are precursors for aranorosin synthesis. Model studies have been carried out to investigate cyclohexadienone epoxidation: dimethyldioxirane has been found to produce mono- 7, 8 and diepoxides 9, 10 in good overall yield.

Original language	English
Pages (from-to)	201-203
Number of pages	3
Journal	Synlett
Issue number	3
Publication status	Published - Mar 1992

Keywords

PSEUDOARACHNIOTUS-ROSEUS
DIMETHYLDIOXIRANE
OXIDATIONS

Cite this

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title = "SYNTHETIC STUDIES TOWARDS ARANOROSIN",

abstract = "Hypervalent iodine reagents have been employed for the conversion of tyrosine derivatives 4a-d, 5 into 3-substituted 1-oxaspiro[4,5]deca-6,9-diene-2,8-diones 3a-d, 6, which are precursors for aranorosin synthesis. Model studies have been carried out to investigate cyclohexadienone epoxidation: dimethyldioxirane has been found to produce mono- 7, 8 and diepoxides 9, 10 in good overall yield.",

keywords = "PSEUDOARACHNIOTUS-ROSEUS, DIMETHYLDIOXIRANE, OXIDATIONS",

author = "A MCKILLOP and L MCLAREN and TAYLOR, {R J K} and WATSON, {R J} and N LEWIS",

year = "1992",

month = mar,

language = "English",

pages = "201--203",

journal = "Synlett",

issn = "1437-2096",

publisher = "Georg Thieme Verlag",

number = "3",

}

TY - JOUR

T1 - SYNTHETIC STUDIES TOWARDS ARANOROSIN

AU - MCKILLOP, A

AU - MCLAREN, L

AU - TAYLOR, R J K

AU - WATSON, R J

AU - LEWIS, N

PY - 1992/3

Y1 - 1992/3

N2 - Hypervalent iodine reagents have been employed for the conversion of tyrosine derivatives 4a-d, 5 into 3-substituted 1-oxaspiro[4,5]deca-6,9-diene-2,8-diones 3a-d, 6, which are precursors for aranorosin synthesis. Model studies have been carried out to investigate cyclohexadienone epoxidation: dimethyldioxirane has been found to produce mono- 7, 8 and diepoxides 9, 10 in good overall yield.

AB - Hypervalent iodine reagents have been employed for the conversion of tyrosine derivatives 4a-d, 5 into 3-substituted 1-oxaspiro[4,5]deca-6,9-diene-2,8-diones 3a-d, 6, which are precursors for aranorosin synthesis. Model studies have been carried out to investigate cyclohexadienone epoxidation: dimethyldioxirane has been found to produce mono- 7, 8 and diepoxides 9, 10 in good overall yield.

KW - PSEUDOARACHNIOTUS-ROSEUS

KW - DIMETHYLDIOXIRANE

KW - OXIDATIONS

M3 - Comment/debate

SN - 1437-2096

SP - 201

EP - 203

JO - Synlett

JF - Synlett

IS - 3

ER -