Synthetic Studies towards the Africanane Sesquiterpenes via the Cope Rearrangement of gem -Dimethyl-Substituted Divinyl Cyclopropanes

Jonathan D. Osler, William P. Unsworth*, Richard J K Taylor

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The Cope rearrangement of gem-dimethyl-substituted divinylcyclopropanes has been used to construct functionalised cycloheptadienes. These scaffolds have been further elaborated to furnish advanced intermediates en route to africanane sesquiterpene natural products, most notably pyxidatol C.

Original languageEnglish
Pages (from-to)70-74
Number of pages5
Issue number1
Early online date24 Aug 2015
Publication statusPublished - 4 Jan 2016

Bibliographical note

© Georg Thieme Verlag. This is an author produced version of a paper published in Synlett. Uploaded in accordance with the publisher's self-archiving policy.


  • africananes.
  • cyclopropanes
  • natural products
  • pericyclic reactions
  • pyxidatol C

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