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Tandem oxidation sequence to prepare ethyl (E)-4,5-dioxo-2-hexadecenoate: A formal synthesis of podoscyphic acid

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JournalSYNTHETIC COMMUNICATIONS
DatePublished - 2005
Issue number22
Volume35
Number of pages9
Pages (from-to)2859-2867
Original languageEnglish

Abstract

A tandem oxidation reaction has been utilized to prepare ethyl (E)-4,5-dioxo-2-hexadecenoate, the immediate precusor to the antiviral fungal metabolite podoscyphic acid.

    Research areas

  • in situ oxidation, in situ oxidation-Wittig reaction, manganese dioxide, podoscyphic acid, MANGANESE-DIOXIDE, WITTIG REACTIONS

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