New free-radical cyclisation and translocation approaches to the tricyclic mitomycin ring system have been developed. These convergent approaches involve either a tandem 5-endol-5-exo radical cyclisation or alternatively, a 1,6-hydrogen-atom transfer followed by 5-exo cyclisation sequence.
|Number of pages||4|
|Publication status||Published - Sep 2002|
- radical reactions
- tandem reactions