The cross-domain functional organisation of posterior lateral temporal cortex: Insights from ALE meta-analyses of seven cognitive domains spanning 12000 participants

Victoria J. Hodgson; Matthew A. Lambon Ralph; Rebecca Louise Jackson

doi:10.1093/cercor/bhac394

The cross-domain functional organisation of posterior lateral temporal cortex: Insights from ALE meta-analyses of seven cognitive domains spanning 12000 participants

Victoria J. Hodgson^*, Matthew A. Lambon Ralph, Rebecca Louise Jackson

^*Corresponding author for this work

Psychology

Research output: Contribution to journal › Article › peer-review

Abstract

The posterior lateral temporal cortex is implicated in many verbal, nonverbal and social cognitive domains and processes. Yet without directly comparing these disparate domains, the region’s organisation remains unclear; do distinct processes engage discrete subregions, or could different domains engage shared neural correlates and processes? Here, using activation likelihood estimation meta-analyses, the bilateral posterior lateral temporal cortex subregions engaged in seven domains were directly compared. These domains comprised semantics, semantic control, phonology, biological motion, face processing, theory of mind, and representation of tools. Whilst phonology and biological motion were predominantly associated with distinct regions, other domains implicated overlapping areas, perhaps due to shared underlying processes. Theory of
mind recruited regions implicated in semantic representation, tools engaged semantic control areas, and faces engaged subregions for biological motion and theory of mind. This cross-domain approach provides insight into how posterior lateral temporal cortex is organised and why.

Original language	English
Article number	bhac394
Number of pages	17
Journal	Cerebral Cortex
DOIs	https://doi.org/10.1093/cercor/bhac394
Publication status	Published - 20 Oct 2022

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10.1093/cercor/bhac394Licence: CC BY

The cross-domain functional organization of posterior lateral temporal cortex: insights from ALE meta-analyses of 7 cognitive domains spanning 12,000 participants
© The Author(s) 2022
Final published version, 1.8 MBLicence: CC BY

Cite this

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