The first total synthesis of a member of the manumycin family of antibiotics: Alisamycin

L  Alcaraz; G  Macdonald; I  Kapfer; N J  Lewis; R J K  Taylor

The first total synthesis of a member of the manumycin family of antibiotics: Alisamycin

L Alcaraz, G Macdonald, I Kapfer, N J Lewis, R J K Taylor

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The development of a general synthetic route to the manumycin family of antibiotics is described and exemplified by the first total synthesis of alisamycin in racemic form. Copyright (C) 1996 Elsevier Science Ltd

Original language	English
Pages (from-to)	6619-6622
Number of pages	4
Journal	Tetrahedron Letters
Volume	37
Issue number	36
Publication status	Published - 2 Sept 1996

Keywords

STREPTOMYCES SP K106
RAS FARNESYLTRANSFERASE INHIBITORS
STRUCTURE ELUCIDATION
BIOLOGICAL PROPERTIES
METABOLIC PRODUCTS
ASUKAMYCIN
NISAMYCIN
STEREOCHEMISTRY
MICROORGANISMS
BIOSYNTHESIS

Cite this

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title = "The first total synthesis of a member of the manumycin family of antibiotics: Alisamycin",

abstract = "The development of a general synthetic route to the manumycin family of antibiotics is described and exemplified by the first total synthesis of alisamycin in racemic form. Copyright (C) 1996 Elsevier Science Ltd",

keywords = "STREPTOMYCES SP K106, RAS FARNESYLTRANSFERASE INHIBITORS, STRUCTURE ELUCIDATION, BIOLOGICAL PROPERTIES, METABOLIC PRODUCTS, ASUKAMYCIN, NISAMYCIN, STEREOCHEMISTRY, MICROORGANISMS, BIOSYNTHESIS",

author = "L Alcaraz and G Macdonald and I Kapfer and Lewis, {N J} and Taylor, {R J K}",

year = "1996",

month = sep,

day = "2",

language = "English",

volume = "37",

pages = "6619--6622",

journal = "Tetrahedron Letters",

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TY - JOUR

T1 - The first total synthesis of a member of the manumycin family of antibiotics: Alisamycin

AU - Alcaraz, L

AU - Macdonald, G

AU - Kapfer, I

AU - Lewis, N J

AU - Taylor, R J K

PY - 1996/9/2

Y1 - 1996/9/2

N2 - The development of a general synthetic route to the manumycin family of antibiotics is described and exemplified by the first total synthesis of alisamycin in racemic form. Copyright (C) 1996 Elsevier Science Ltd

AB - The development of a general synthetic route to the manumycin family of antibiotics is described and exemplified by the first total synthesis of alisamycin in racemic form. Copyright (C) 1996 Elsevier Science Ltd

KW - STREPTOMYCES SP K106

KW - RAS FARNESYLTRANSFERASE INHIBITORS

KW - STRUCTURE ELUCIDATION

KW - BIOLOGICAL PROPERTIES

KW - METABOLIC PRODUCTS

KW - ASUKAMYCIN

KW - NISAMYCIN

KW - STEREOCHEMISTRY

KW - MICROORGANISMS

KW - BIOSYNTHESIS

M3 - Article

SN - 0040-4039

VL - 37

SP - 6619

EP - 6622

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 36

ER -