Projects per year
Abstract
Technological innovations such as Next Generation Sequencing and DNA hybridisation enrichment have resulted in multi-fold increases in both the quantity of ancient DNA sequence data and the time depth for DNA retrieval. To date, over 30 ancient genomes have been sequenced, moving from 0.7x coverage (mammoth) in 2008 to more than 50x coverage (Neanderthal) this year. Studies of rapid evolutionary changes, such as the evolution and spread of pathogens and the genetic responses of hosts, or the genetics of domestication and climatic adaptation, are developing swiftly and the importance of palaeogenomics for investigating evolutionary processes during the last million years is likely to increase considerably. However, these new datasets require new methods of data processing and analysis, as well as conceptual changes in interpreting the results. In this review we highlight important areas of future technical and conceptual progress and discuss research topics in the rapidly growing field of palaeogenomics.
Original language | English |
---|---|
Pages (from-to) | 284-293 |
Number of pages | 10 |
Journal | Bioessays |
Volume | 37 |
Issue number | 3 |
DOIs | |
Publication status | Published - Mar 2015 |
Projects
- 2 Finished
-
ORCA, MC IEF Camilla Speller: Optimizing Research Tools for cetaceans in Archaeology
Collins, M. J. & Speller, C. F.
10/09/12 → 9/09/14
Project: Research project (funded) › Research
-
CodeX: Decoding domesticate DNA in archaeological bone and manuscripts
1/07/12 → 30/06/18
Project: Research project (funded) › Research