The in situ oxidation-Wittig reaction of alpha-hydroxyketones

K A Runcie, R J K Taylor

Research output: Contribution to journalArticlepeer-review


In situ oxidation-Wittig methodology has been applied to a alpha-hydroxyketones avoiding the problems normally associated with alpha-ketoaldehydes; the procedure is practically simple, and in many cases gives high yields of the product gamma-ketocrotonates; the procedure has also been successfully utilised with ethyl glycolate and glycolaldehyde dimer.

Original languageEnglish
Pages (from-to)974-975
Number of pages2
JournalChemical Communications
Issue number9
Publication statusPublished - 2002



Cite this