The negative BOLD signal unmasked

Alex R Wade

The negative BOLD signal unmasked

Psychology

Research output: Contribution to journal › Article › peer-review

Abstract

Many fMRI experiments show regions of cortex that seem to respond in antiphase with the primary stimulus. In this issue of Neuron, Shmuel et al. show that this "negative BOLD response" is spatially and temporally linked to reductions in blood flow. By combining BOLD and blood flow data to model the energy consumption in cortex, they conclude that the NBR is primarily due to active neuronal inhibition.

Original language	English
Pages (from-to)	993-5
Number of pages	3
Journal	Neuron
Volume	36
Issue number	6
Publication status	Published - 2002

Keywords

Cerebral Cortex
Cerebrovascular Circulation
Energy Metabolism
Evoked Potentials
Humans
Magnetic Resonance Imaging
Models, Neurological
Neural Inhibition
Neurons

Cite this

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KW - Cerebral Cortex

KW - Cerebrovascular Circulation

KW - Energy Metabolism

KW - Evoked Potentials

KW - Humans

KW - Magnetic Resonance Imaging

KW - Models, Neurological

KW - Neural Inhibition

KW - Neurons

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