The neural correlates of semantic control revisited

TY - JOUR

T1 - The neural correlates of semantic control revisited

AU - Jackson, Rebecca L.

N1 - Funding Information: This work was supported by a British Academy Postdoctoral Fellowship awarded to RLJ ( pf170068 ) and Medical Research Council intramural funding ( MC_UU_00005/18 ). The funders had no role in the design, analysis or interpretation of the results or the writing of the manuscript. Publisher Copyright: © 2020 The Author

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Semantic control, the ability to selectively access and manipulate meaningful information on the basis of context demands, is a critical component of semantic cognition. The precise neural correlates of semantic control are disputed, with particular debate surrounding parietal involvement, the spatial extent of the posterior temporal contribution and network lateralisation. Here semantic control is revisited, utilising improved analysis techniques and a decade of additional data to refine our understanding of the network. A meta-analysis of 925 peaks over 126 contrasts illuminated a left-focused network consisting of inferior frontal gyrus, posterior middle temporal gyrus, posterior inferior temporal gyrus and dorsomedial prefrontal cortex. This extended the temporal region implicated, and found no parietal involvement. Although left-lateralised overall, relative lateralisation varied across the implicated regions. Supporting analyses confirmed the multimodal nature of the semantic control network and situated it within the wider set of regions implicated in semantic cognition.

AB - Semantic control, the ability to selectively access and manipulate meaningful information on the basis of context demands, is a critical component of semantic cognition. The precise neural correlates of semantic control are disputed, with particular debate surrounding parietal involvement, the spatial extent of the posterior temporal contribution and network lateralisation. Here semantic control is revisited, utilising improved analysis techniques and a decade of additional data to refine our understanding of the network. A meta-analysis of 925 peaks over 126 contrasts illuminated a left-focused network consisting of inferior frontal gyrus, posterior middle temporal gyrus, posterior inferior temporal gyrus and dorsomedial prefrontal cortex. This extended the temporal region implicated, and found no parietal involvement. Although left-lateralised overall, relative lateralisation varied across the implicated regions. Supporting analyses confirmed the multimodal nature of the semantic control network and situated it within the wider set of regions implicated in semantic cognition.

KW - ALE meta-analysis

KW - Control

KW - Executive processing

KW - Semantic cognition

KW - Semantic control

UR - http://www.scopus.com/inward/record.url?scp=85092615857&partnerID=8YFLogxK

U2 - 10.1016/j.neuroimage.2020.117444

DO - 10.1016/j.neuroimage.2020.117444

M3 - Article

C2 - 33059049

AN - SCOPUS:85092615857

SN - 1053-8119

VL - 224

JO - Neuroimage

JF - Neuroimage

M1 - 117444

ER -