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The prevalence of diabetes mellitus and abnormal glucose metabolism in the inpatient psychiatric setting: A systematic review and meta-analysis

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  • Emmert Roberts
  • Leah Jones
  • Alexandra Blackman
  • Thomas Dewhurst
  • Faith Matcham
  • Carol Kan
  • Omar Mustafa
  • Toral Thomas
  • Najma Siddiqi
  • Khalida Ismail
  • Hermione Price


Publication details

JournalGeneral hospital psychiatry
DateAccepted/In press - 8 Jan 2017
DateE-pub ahead of print - 11 Jan 2017
DatePublished (current) - 1 Mar 2017
Number of pages9
Pages (from-to)76-84
Early online date11/01/17
Original languageEnglish


Objective To systematically determine the prevalence of diabetes mellitus (DM), impaired fasting glucose (IFG), and impaired glucose tolerance (IGT) in psychiatric inpatients and explore the impact of patient and study variables on prevalence estimates. Method We searched EMBASE, PsychINFO, Medline and CENTRAL from database inception until 1st December 2015. We included studies of any design reporting prevalence of abnormal glucose metabolism in any adult psychiatric inpatients. We conducted a random effects meta-analysis to generate pooled prevalence estimates. Chi-square tests compared differences within categorical variables (inpatient setting, continent of study and patient diagnostic category) and Spearman's correlation analyses assessed the impact of linear variables (age, year of data collection and study quality). Study quality was assessed using an adapted Newcastle-Ottawa Scale. Results 36 study reports representing 42 unique cohorts were included. Across all studies prevalence of unspecified type DM was 10% (95%CI: 9–12), of T1DM was 1% (0–1), of T2DM was 9% (6–13), of IFG 18% (8–28), and of IGT was 22% (16–28). These estimates were not affected by study quality. Conclusions All estimates are higher compared to the general population. Mental health professionals should be aware of this elevated prevalence to improve screening and management of abnormal glucose metabolism.

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© 2017 Elsevier Inc. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy.

    Research areas

  • Diabetes mellitus, Inpatient psychiatry, Serious mental illness

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