The Right Light – De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry

Gideon James Grogan; Holly Bonfield; Kayleigh Mercer; Alba Diaz-Rodriguez; Gemma Cook; Blandine McKay; Pawel Slade; George Taylor; Wei Xiang Ooi; Jason Williams; Jack Roberts; John Murphy; Luca Schmermund; Wolfgang Kroutil; Tamara Mielke; Jared Cartwright; Lee Edwards

doi:10.1002/cptc.201900203

The Right Light – De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry

Gideon James Grogan, Holly Bonfield, Kayleigh Mercer, Alba Diaz-Rodriguez, Gemma Cook, Blandine McKay, Pawel Slade, George Taylor, Wei Xiang Ooi, Jason Williams, Jack Roberts, John Murphy, Luca Schmermund, Wolfgang Kroutil, Tamara Mielke, Jared Cartwright, Lee Edwards

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Having identified inconsistencies when repeating literature examples of photochemical transformations and difficulties recreating experimental setups, we devised several criteria that an ideal labscale reactor should achieve. Herein, we introduce a versatile photoreactor for high throughput screening, preparative scale batch reactions and continuous processing, all with a single light source. The reactor utilizes interchangeable arrays of pseudo-monochromatic high-power LEDs in a range of synthetically useful wavelengths, combined with excellent temperature control. Moreover, light intensity can be modulated in an accurate and straightforward manner. This system has subsequently been tested on a range of literature methodologies.

Original language	English
Journal	Chemphotochem
Early online date	15 Aug 2019
DOIs	https://doi.org/10.1002/cptc.201900203
Publication status	E-pub ahead of print - 15 Aug 2019

Bibliographical note

This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

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10.1002/cptc.201900203

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Cite this

Grogan, G. J., Bonfield, H., Mercer, K., Diaz-Rodriguez, A., Cook, G., McKay, B., Slade, P., Taylor, G., Ooi, W. X., Williams, J., Roberts, J., Murphy, J., Schmermund, L., Kroutil, W., Mielke, T., Cartwright, J., & Edwards, L. (2019). The Right Light – De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry. Chemphotochem. https://doi.org/10.1002/cptc.201900203

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title = "The Right Light – De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry",

abstract = "Having identified inconsistencies when repeating literature examples of photochemical transformations and difficulties recreating experimental setups, we devised several criteria that an ideal labscale reactor should achieve. Herein, we introduce a versatile photoreactor for high throughput screening, preparative scale batch reactions and continuous processing, all with a single light source. The reactor utilizes interchangeable arrays of pseudo-monochromatic high-power LEDs in a range of synthetically useful wavelengths, combined with excellent temperature control. Moreover, light intensity can be modulated in an accurate and straightforward manner. This system has subsequently been tested on a range of literature methodologies. ",

author = "Grogan, {Gideon James} and Holly Bonfield and Kayleigh Mercer and Alba Diaz-Rodriguez and Gemma Cook and Blandine McKay and Pawel Slade and George Taylor and Ooi, {Wei Xiang} and Jason Williams and Jack Roberts and John Murphy and Luca Schmermund and Wolfgang Kroutil and Tamara Mielke and Jared Cartwright and Lee Edwards",

note = "This is an author-produced version of the published paper. Uploaded in accordance with the publisher{\textquoteright}s self-archiving policy. Further copying may not be permitted; contact the publisher for details. ",

year = "2019",

month = aug,

day = "15",

doi = "10.1002/cptc.201900203",

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Grogan, GJ, Bonfield, H, Mercer, K, Diaz-Rodriguez, A, Cook, G, McKay, B, Slade, P, Taylor, G, Ooi, WX, Williams, J, Roberts, J, Murphy, J, Schmermund, L, Kroutil, W, Mielke, T, Cartwright, J & Edwards, L 2019, 'The Right Light – De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry', Chemphotochem. https://doi.org/10.1002/cptc.201900203

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T1 - The Right Light – De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry

AU - Grogan, Gideon James

AU - Bonfield, Holly

AU - Mercer, Kayleigh

AU - Diaz-Rodriguez, Alba

AU - Cook, Gemma

AU - McKay, Blandine

AU - Slade, Pawel

AU - Taylor, George

AU - Ooi, Wei Xiang

AU - Williams, Jason

AU - Roberts, Jack

AU - Murphy, John

AU - Schmermund, Luca

AU - Kroutil, Wolfgang

AU - Mielke, Tamara

AU - Cartwright, Jared

AU - Edwards, Lee

N1 - This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.

PY - 2019/8/15

Y1 - 2019/8/15

N2 - Having identified inconsistencies when repeating literature examples of photochemical transformations and difficulties recreating experimental setups, we devised several criteria that an ideal labscale reactor should achieve. Herein, we introduce a versatile photoreactor for high throughput screening, preparative scale batch reactions and continuous processing, all with a single light source. The reactor utilizes interchangeable arrays of pseudo-monochromatic high-power LEDs in a range of synthetically useful wavelengths, combined with excellent temperature control. Moreover, light intensity can be modulated in an accurate and straightforward manner. This system has subsequently been tested on a range of literature methodologies.

AB - Having identified inconsistencies when repeating literature examples of photochemical transformations and difficulties recreating experimental setups, we devised several criteria that an ideal labscale reactor should achieve. Herein, we introduce a versatile photoreactor for high throughput screening, preparative scale batch reactions and continuous processing, all with a single light source. The reactor utilizes interchangeable arrays of pseudo-monochromatic high-power LEDs in a range of synthetically useful wavelengths, combined with excellent temperature control. Moreover, light intensity can be modulated in an accurate and straightforward manner. This system has subsequently been tested on a range of literature methodologies.

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DO - 10.1002/cptc.201900203

M3 - Article

JO - Chemphotochem

JF - Chemphotochem

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