The rise in computational systems biology approaches for understanding NF-κB signaling dynamics

Richard Alun Williams, Jon Timmis, Eva Qwarnstrom

Research output: Contribution to journalComment/debatepeer-review


A study by Cheng et al. in this issue of Science Signaling highlights the distinct single-cell signaling characteristics conferred by pathways mediated by the adaptor proteins MyD88 and TRIF in the TLR4-dependent activation of the transcription factor nuclear factor κB (NF-κB).
Original languageEnglish
Article numberfs13
JournalScience Signaling
Issue number385
Publication statusPublished - 14 Jul 2015


  • computational modelling
  • NF-kappa B

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