The rise in computational systems biology approaches for understanding NF-κB signaling dynamics

TY - JOUR

T1 - The rise in computational systems biology approaches for understanding NF-κB signaling dynamics

AU - Williams, Richard Alun

AU - Timmis, Jon

AU - Qwarnstrom, Eva

PY - 2015/7/14

Y1 - 2015/7/14

N2 - A study by Cheng et al. in this issue of Science Signaling highlights the distinct single-cell signaling characteristics conferred by pathways mediated by the adaptor proteins MyD88 and TRIF in the TLR4-dependent activation of the transcription factor nuclear factor κB (NF-κB).

AB - A study by Cheng et al. in this issue of Science Signaling highlights the distinct single-cell signaling characteristics conferred by pathways mediated by the adaptor proteins MyD88 and TRIF in the TLR4-dependent activation of the transcription factor nuclear factor κB (NF-κB).

KW - computational modelling

KW - NF-kappa B

U2 - 10.1126/scisignal.aac6503

DO - 10.1126/scisignal.aac6503

M3 - Comment/debate

SN - 1937-9145

VL - 8

JO - Science Signaling

JF - Science Signaling

IS - 385

M1 - fs13

ER -