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The Role of Explainability in Assuring Safety of Machine Learning in Healthcare

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JournalIEEE Transactions on Emerging Topics in Computational Intelligence
DateE-pub ahead of print - 5 May 2022
Number of pages14
Original languageEnglish

Abstract

Established approaches to assuring safety-critical systems and software are difficult to apply to systems employing ML where there is no clear, pre-defined specification against which to assess validity. This problem is exacerbated by the opaque nature of ML where the learnt model is not amenable to human scrutiny. XAI methods have been proposed to tackle this issue by producing human-interpretable representations of ML models which can help users to gain confidence and build trust in the ML system. However, little work explicitly investigates the role of explainability for safety assurance in the context of ML development. This paper identifies ways in which XAI methods can contribute to safety assurance of ML-based systems. It then uses a concrete ML-based clinical decision support system, concerning weaning of patients from mechanical ventilation, to demonstrate how XAI methods can be employed to produce evidence to support safety assurance. The results are also represented in a safety argument to show where, and in what way, XAI methods can contribute to a safety case. Overall, we conclude that XAI methods have a valuable role in safety assurance of ML-based systems in healthcare but that they are not sufficient in themselves to assure safety.

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