The role of humidity and UV-C emission in the inactivation of B. subtilis spores during atmospheric-pressure dielectric barrier discharge treatment

Friederike Kogelheide, Farina Voigt, Bastian Hillebrand, Ralf Moeller, Felix Fuchs, Andrew R. Gibson, Peter Awakowicz, Katharina Stapelmann, Marcel Fiebrandt

Research output: Contribution to journalArticlepeer-review

Abstract

Experiments are performed to assess the inactivation of Bacillus subtilis spores using a non-thermal atmospheric-pressure dielectric barrier discharge. The plasma source used in this study is mounted inside a vacuum vessel and operated in controlled gas mixtures. In this context, spore inactivation is measured under varying nitrogen/oxygen and humidity content and compared to spore inactivation using ambient air. Operating the dielectric barrier discharge in a sealed vessel offers the ability to distinguish between possible spore inactivation mechanisms since different process gas mixtures lead to the formation of distinct reactive species. The UV irradiance and the ozone density within the plasma volume are determined applying spectroscopic diagnostics with neither found to fully correlate with spore inactivation. It is found that spore inactivation is most strongly correlated with the humidity content in the feed gas, implying that reactive species formed, either directly or indirectly, from water molecules are strong mediators of spore inactivation.

Original languageEnglish
Article number295201
Number of pages14
JournalJournal of Physics D: Applied Physics
Volume53
Issue number29
DOIs
Publication statusPublished - 19 May 2020

Bibliographical note

Publisher Copyright:
© 2020 The Author(s). Published by IOP Publishing Ltd.

Keywords

  • atmospheric pressure
  • Bacillus subtilis spores
  • controlled atmosphere
  • dielectric barrier discharge
  • inactivation experiments
  • spectroscopy

Cite this