The Spatialiased Sonification of Drug-Enzyme Interactions

Richard J. McIlraith; Paul H Walton; J.S. Brereton

The Spatialiased Sonification of Drug-Enzyme Interactions

Richard J. McIlraith, Paul H Walton, J.S. Brereton

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This paper presents the preliminary work into the creation of an interactive spatial sonification system used to model the interactions between drug molecules and their target biomolecules within the human body. With the aid of sonification and a 3D soundscape, the user is able to optimize these interactions to a much greater precision than the sole use of the current visual model. This system gives a promising means to aid the rapid design of new drug molecules that can interact more strongly with the enzyme’s active site, therefore creating more effective drugs for the treatment of cancer and other diseases. This paper gives a full account of the relevant theory, the techniques used and details of preliminary user testing.

Original language	Undefined/Unknown
Title of host publication	The 21st International Conference on Auditory Display (ICAD 2015)
Place of Publication	Graz, Austria
Pages	323-324
Number of pages	2
Publication status	Published - 2015

Keywords

sonicules

Sonicules: Designing Drugs with Sound
Brereton, J. (Principal investigator), Walton, P. H. (Co-investigator) & Rudnicki, R. (Principal investigator)
1/01/16 → 30/06/16
Project: Other project › Other internal award

Cite this

@inproceedings{5d7eac13cabb4800af3e23f431094cbf,

title = "The Spatialiased Sonification of Drug-Enzyme Interactions",

abstract = "This paper presents the preliminary work into the creation of an interactive spatial sonification system used to model the interactions between drug molecules and their target biomolecules within the human body. With the aid of sonification and a 3D soundscape, the user is able to optimize these interactions to a much greater precision than the sole use of the current visual model. This system gives a promising means to aid the rapid design of new drug molecules that can interact more strongly with the enzyme{\textquoteright}s active site, therefore creating more effective drugs for the treatment of cancer and other diseases. This paper gives a full account of the relevant theory, the techniques used and details of preliminary user testing.",

keywords = "sonicules",

author = "McIlraith, {Richard J.} and Walton, {Paul H} and J.S. Brereton",

year = "2015",

language = "Undefined/Unknown",

pages = "323--324",

booktitle = "The 21st International Conference on Auditory Display (ICAD 2015)",

}

TY - GEN

T1 - The Spatialiased Sonification of Drug-Enzyme Interactions

AU - McIlraith, Richard J.

AU - Walton, Paul H

AU - Brereton, J.S.

PY - 2015

Y1 - 2015

N2 - This paper presents the preliminary work into the creation of an interactive spatial sonification system used to model the interactions between drug molecules and their target biomolecules within the human body. With the aid of sonification and a 3D soundscape, the user is able to optimize these interactions to a much greater precision than the sole use of the current visual model. This system gives a promising means to aid the rapid design of new drug molecules that can interact more strongly with the enzyme’s active site, therefore creating more effective drugs for the treatment of cancer and other diseases. This paper gives a full account of the relevant theory, the techniques used and details of preliminary user testing.

AB - This paper presents the preliminary work into the creation of an interactive spatial sonification system used to model the interactions between drug molecules and their target biomolecules within the human body. With the aid of sonification and a 3D soundscape, the user is able to optimize these interactions to a much greater precision than the sole use of the current visual model. This system gives a promising means to aid the rapid design of new drug molecules that can interact more strongly with the enzyme’s active site, therefore creating more effective drugs for the treatment of cancer and other diseases. This paper gives a full account of the relevant theory, the techniques used and details of preliminary user testing.

KW - sonicules

M3 - Conference contribution

SP - 323

EP - 324

BT - The 21st International Conference on Auditory Display (ICAD 2015)

CY - Graz, Austria

ER -

The Spatialiased Sonification of Drug-Enzyme Interactions

Abstract

Keywords

Projects

Sonicules: Designing Drugs with Sound

Cite this