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From the same journal

THE TRIFLUOROMETHYLATION OF CHLOROAROMATICS USING THE COPPER-CF2BR2 - DIALKYLAMIDE REACTION SYSTEM

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JournalJOURNAL OF FLUORINE CHEMISTRY
DatePublished - Dec 1990
Issue number3
Volume50
Number of pages16
Pages (from-to)411-426
Original languageEnglish

Abstract

The in situ generation of CuCF3 from the reaction of copper, dibromodifluoromethane and either N,N-dimethylformamide or N,N-dimethylacetamide (Burton's reagent) has been used for the direct substitution of chlorine by CF3 in a number of aromatic substrates. Particular attention has been paid to the effects of ring substituents on the efficiency of reaction.

    Research areas

  • SODIUM TRIFLUOROACETATE

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