Thermotropic liquid crystalline glycolipids

J. W. Goodby; Verena Gortz; S. J. Cowling; G. Mackenzie; P. Martin; D. Plusquellec; T. Benvegnu; P. Boullanger; D. Lafont; Y. Queneau; S. Chambert; J. Fitremann

doi:10.1039/b708458g

Thermotropic liquid crystalline glycolipids

J. W. Goodby, Verena Gortz, S. J. Cowling, G. Mackenzie, P. Martin, D. Plusquellec, T. Benvegnu, P. Boullanger, D. Lafont, Y. Queneau, S. Chambert, J. Fitremann

Chemistry

Research output: Contribution to journal › Literature review › peer-review

Abstract

Are the liquid crystalline properties of the materials of living systems important in biological structures, functions, diseases and treatments? There is a growing consciousness that the observed lyotropic, and often thermotropic liquid crystallinity, of many biological materials that possess key biological functionality might be more than curious coincidence. Rather, as the survival of living systems depends on the flexibility and reformability of structures, it seems more likely that it is the combination of softness and structure of the liquid- crystalline state that determines the functionality of biological materials. The richest sources of liquid crystals derived from living systems are found in cell membranes, of these glycolipids are a particularly important class of components. In this critical review, we will examine the relationship between chemical structure and the self- assembling and self- organising properties of glycolipids that ultimately lead to mesophase formation.

Original language	English
Pages (from-to)	1971-2032
Number of pages	62
Journal	Chemical Society Reviews
Volume	36
Issue number	12
DOIs	https://doi.org/10.1039/b708458g
Publication status	Published - 2007

Keywords

OLEFIN CROSS-METATHESIS
D-ERYTHRO-SPHINGOSINE
CATALYZED REGIOSELECTIVE ESTERIFICATION
DIFFERENTIAL SCANNING CALORIMETRY
ARCHAEBACTERIAL MEMBRANE-LIPIDS
SUCROSE HYDROXYALKYL ETHERS
CARBOHYDRATE-BASED MESOGENS
SELF-ORGANIZING PROPERTIES
PHASE-TRANSFER CATALYSIS
METHANOSPIRILLUM-HUNGATEI

Access to Document

10.1039/b708458g

Cite this

@article{dd39a6f8075c448989c5aa465dbd12ab,

title = "Thermotropic liquid crystalline glycolipids",

abstract = "Are the liquid crystalline properties of the materials of living systems important in biological structures, functions, diseases and treatments? There is a growing consciousness that the observed lyotropic, and often thermotropic liquid crystallinity, of many biological materials that possess key biological functionality might be more than curious coincidence. Rather, as the survival of living systems depends on the flexibility and reformability of structures, it seems more likely that it is the combination of softness and structure of the liquid- crystalline state that determines the functionality of biological materials. The richest sources of liquid crystals derived from living systems are found in cell membranes, of these glycolipids are a particularly important class of components. In this critical review, we will examine the relationship between chemical structure and the self- assembling and self- organising properties of glycolipids that ultimately lead to mesophase formation.",

keywords = "OLEFIN CROSS-METATHESIS, D-ERYTHRO-SPHINGOSINE, CATALYZED REGIOSELECTIVE ESTERIFICATION, DIFFERENTIAL SCANNING CALORIMETRY, ARCHAEBACTERIAL MEMBRANE-LIPIDS, SUCROSE HYDROXYALKYL ETHERS, CARBOHYDRATE-BASED MESOGENS, SELF-ORGANIZING PROPERTIES, PHASE-TRANSFER CATALYSIS, METHANOSPIRILLUM-HUNGATEI",

author = "Goodby, {J. W.} and Verena Gortz and Cowling, {S. J.} and G. Mackenzie and P. Martin and D. Plusquellec and T. Benvegnu and P. Boullanger and D. Lafont and Y. Queneau and S. Chambert and J. Fitremann",

year = "2007",

doi = "10.1039/b708458g",

language = "English",

volume = "36",

pages = "1971--2032",

journal = "Chemical Society Reviews",

publisher = "The Royal Society of Chemistry",

number = "12",

}

TY - JOUR

T1 - Thermotropic liquid crystalline glycolipids

AU - Goodby, J. W.

AU - Gortz, Verena

AU - Cowling, S. J.

AU - Mackenzie, G.

AU - Martin, P.

AU - Plusquellec, D.

AU - Benvegnu, T.

AU - Boullanger, P.

AU - Lafont, D.

AU - Queneau, Y.

AU - Chambert, S.

AU - Fitremann, J.

PY - 2007

Y1 - 2007

N2 - Are the liquid crystalline properties of the materials of living systems important in biological structures, functions, diseases and treatments? There is a growing consciousness that the observed lyotropic, and often thermotropic liquid crystallinity, of many biological materials that possess key biological functionality might be more than curious coincidence. Rather, as the survival of living systems depends on the flexibility and reformability of structures, it seems more likely that it is the combination of softness and structure of the liquid- crystalline state that determines the functionality of biological materials. The richest sources of liquid crystals derived from living systems are found in cell membranes, of these glycolipids are a particularly important class of components. In this critical review, we will examine the relationship between chemical structure and the self- assembling and self- organising properties of glycolipids that ultimately lead to mesophase formation.

AB - Are the liquid crystalline properties of the materials of living systems important in biological structures, functions, diseases and treatments? There is a growing consciousness that the observed lyotropic, and often thermotropic liquid crystallinity, of many biological materials that possess key biological functionality might be more than curious coincidence. Rather, as the survival of living systems depends on the flexibility and reformability of structures, it seems more likely that it is the combination of softness and structure of the liquid- crystalline state that determines the functionality of biological materials. The richest sources of liquid crystals derived from living systems are found in cell membranes, of these glycolipids are a particularly important class of components. In this critical review, we will examine the relationship between chemical structure and the self- assembling and self- organising properties of glycolipids that ultimately lead to mesophase formation.

KW - OLEFIN CROSS-METATHESIS

KW - D-ERYTHRO-SPHINGOSINE

KW - CATALYZED REGIOSELECTIVE ESTERIFICATION

KW - DIFFERENTIAL SCANNING CALORIMETRY

KW - ARCHAEBACTERIAL MEMBRANE-LIPIDS

KW - SUCROSE HYDROXYALKYL ETHERS

KW - CARBOHYDRATE-BASED MESOGENS

KW - SELF-ORGANIZING PROPERTIES

KW - PHASE-TRANSFER CATALYSIS

KW - METHANOSPIRILLUM-HUNGATEI

U2 - 10.1039/b708458g

DO - 10.1039/b708458g

M3 - Literature review

VL - 36

SP - 1971

EP - 2032

JO - Chemical Society Reviews

JF - Chemical Society Reviews

IS - 12

ER -