Three-Dimensional Visualisation of Skeletal Cavities

Alessio Veneziano, Antonio Profico

Research output: Contribution to journalArticlepeer-review


Bones contain spaces within them. The extraction and the analysis of those cavities are crucial in the study of bone tissue function and can inform about pathologies or past traumatic events. The use of medical imaging techniques allows a non-invasive visualisation of skeletal cavities opening a new frontier in medical inspection and diagnosis. Here, we report the application of a new mesh-based approach for the isolation of skeletal cavities of different size and geometrical structure. We apply a mesh-based approach to extract (i) the main virtual cavities inside the human skull, (ii) a complete human endocast, (iii) the inner vasculature of the malleus bone and (iv) the medullary of a human femur. The detailed description of the mesh-based isolation method and its pioneristic application to four different case-studies show the potential of this approach in medical visualisation.

Original languageEnglish
Pages (from-to)73-83
Number of pages11
JournalAdvances in experimental medicine and biology
Publication statusPublished - 11 Dec 2019


  • Anatomy/methods
  • Bone and Bones/anatomy & histology
  • Data Visualization
  • Humans
  • Imaging, Three-Dimensional

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