Projects per year
Activity-based protein profiling has emerged as a powerful tool for visualizing glycosidases in complex biological samples. Several configurational cyclophellitol isomers have been shown to display high selectivity as probes for glycosidases processing substrates featuring the same configuration. Here, a set of deoxygenated cyclophellitols are presented which enable inter-class profiling of [small beta]-glucosidases and [small beta]-galactosidases.
|Number of pages||5|
|Early online date||6 Nov 2017|
|Publication status||E-pub ahead of print - 6 Nov 2017|
Bibliographical note© 2017, The Author(s).
- 1 Finished
Glycosylation: Programmes for Observation, Inhibition & Structure-based Exploitation of key carbohydrate-active enzymes
1/05/13 → 30/04/19
Project: Research project (funded) › Research