Toxicodynamic assumptions in ecotoxicological hazard models

Roman Ashauer; Colin D. Brown

Toxicodynamic assumptions in ecotoxicological hazard models

Environment and Geography

Research output: Contribution to journal › Article › peer-review

Abstract

Existing toxicokinetic and toxicodynamic models and dynamic formulations of popular ecotoxicological concepts (e.g., the critical body residue concept) are examined. Their underlying assumptions about speed of recovery and thresholds are clarified, and a rigorous mathematical treatment shows that they can all be placed within a unifying framework. Such analysis aids in the selection of appropriate ecotoxicological models.

Original language	English
Pages (from-to)	1817-1821
Number of pages	5
Journal	Environmental Toxicology and Chemistry
Volume	27
Issue number	8
Publication status	Published - Aug 2008

Keywords

hazard models
risk assessment
tissue residue
toxicity
DEBtox
DEPENDENT PAH TOXICITY
DOSE-EFFECT MODEL
HYALELLA-AZTECA
ORGANOPHOSPHORUS PESTICIDES
TOXICOKINETIC MODEL
AQUATIC TOXICITY
PULSED EXPOSURE
GAMMARUS-PULEX
TIME
SURVIVAL

Cite this

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KW - tissue residue

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KW - DOSE-EFFECT MODEL

KW - HYALELLA-AZTECA

KW - ORGANOPHOSPHORUS PESTICIDES

KW - TOXICOKINETIC MODEL

KW - AQUATIC TOXICITY

KW - PULSED EXPOSURE

KW - GAMMARUS-PULEX

KW - TIME

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JO - Environmental Toxicology and Chemistry

JF - Environmental Toxicology and Chemistry

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ER -

Toxicodynamic assumptions in ecotoxicological hazard models

Abstract

Keywords

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