Transition-Metal-Mediated Routes to 3,3-Disubstituted Oxindoles through Anilide Cyclisation

Johannes E. M. N. Klein, Richard J. K. Taylor

Research output: Contribution to journalLiterature reviewpeer-review


This review describes transition-metal-catalysed and -mediated processes for the preparation of oxindoles from anilides through C(3)C(3a) bond formation. Traditional methods, such as the Heck reaction, and recent developments, including direct ArH coupling processes, are presented, as are applications in natural product synthesis.

Original languageEnglish
Pages (from-to)6821-6841
Number of pages21
JournalEuropean Journal of Organic Chemistry
Issue number34
Publication statusPublished - Dec 2011

Cite this