Transition-Metal-Mediated Routes to 3,3-Disubstituted Oxindoles through Anilide Cyclisation

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Research output: Contribution to journal › Literature review › peer-review

Published copy (DOI)

10.1002/ejoc.201100836

Author(s)

Johannes E. M. N. Klein
Richard J. K. Taylor

Department/unit(s)

Chemistry

Publication details

Journal	European Journal of Organic Chemistry
Date	Published - Dec 2011
Issue number	34
Number of pages	21
Pages (from-to)	6821-6841
Original language	English

Abstract

This review describes transition-metal-catalysed and -mediated processes for the preparation of oxindoles from anilides through C(3)C(3a) bond formation. Traditional methods, such as the Heck reaction, and recent developments, including direct ArH coupling processes, are presented, as are applications in natural product synthesis.

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