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Transition-Metal-Mediated Routes to 3,3-Disubstituted Oxindoles through Anilide Cyclisation

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JournalEuropean Journal of Organic Chemistry
DatePublished - Dec 2011
Issue number34
Number of pages21
Pages (from-to)6821-6841
Original languageEnglish

Abstract

This review describes transition-metal-catalysed and -mediated processes for the preparation of oxindoles from anilides through C(3)C(3a) bond formation. Traditional methods, such as the Heck reaction, and recent developments, including direct ArH coupling processes, are presented, as are applications in natural product synthesis.

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