Treatment and rehabilitation of Long COVID: A scope of the literature. Update October 2024

Gary Austin Raine; Claire Louise Khouja; Melissa Harden; Katy Sutcliffe; Amanda Jayne Sowden

Treatment and rehabilitation of Long COVID: A scope of the literature. Update October 2024

Gary Austin Raine, Claire Louise Khouja, Melissa Harden, Katy Sutcliffe, Amanda Jayne Sowden

Centre for Reviews and Dissemination

Research output: Book/Report › Commissioned report

Abstract

• We identified 16 randomised controlled trials published between June and September 2024 that were focused on Long COVID treatment or rehabilitation. Across our ten reports produced to date, we have identified and assessed 156 trials published between January 2022 and September 2024.
• Eight of the 16 trials focused on treating generalised or multiple symptoms of Long COVID. Three trials focused specifically on respiratory or cardiovascular function or physical fitness, two of which also had a focus on fatigue. One other trial focused specifically on treating fatigue. Two trials focused on treating persistent problems with the sense of smell or taste (olfactory/gustatory dysfunction) and two evaluated treatments for neuropsychological sequela.
• Two trials were rated positively for 12 out of the 13 quality criteria that we assessed and three met 11 criteria. The remaining 11 trials gained a positive rating for between seven and ten criteria.

Original language	English
Place of Publication	London
Publisher	EPPI Centre, UCL Social Research Institute, UCL Institute of Education, University College London
Commissioning body	NIHR Policy Research Programme
Number of pages	26
ISBN (Electronic)	978-1-911605-69-0
Publication status	Published - 20 Nov 2024

Keywords

Long COVID
RCTs
systematic map

Access to Document

LC_treatment_10_Oct24_LO-201124
Authors of the systematic reviews on the EPPI Centre website (http://eppi.ioe.ac.uk/) hold the copyright for the text of their reviews. The EPPI Centre owns the copyright for all material on the website it has developed, including the contents of the databases, manuals, and keywording and data-extraction systems. The centre and authors give permission for users of the site to display and print the contents of the site for their own non-commercial use, providing that the materials are not modified, copyright and other proprietary notices contained in the materials are retained, and the source of the material is cited clearly following the citation details provided. Otherwise, users are not permitted to duplicate, reproduce, re-publish, distribute, or store material from this website without express written permission.
Final published version, 1.3 MBLicence: CC BY-NC

Cite this

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abstract = "• We identified 16 randomised controlled trials published between June and September 2024 that were focused on Long COVID treatment or rehabilitation. Across our ten reports produced to date, we have identified and assessed 156 trials published between January 2022 and September 2024.• Eight of the 16 trials focused on treating generalised or multiple symptoms of Long COVID. Three trials focused specifically on respiratory or cardiovascular function or physical fitness, two of which also had a focus on fatigue. One other trial focused specifically on treating fatigue. Two trials focused on treating persistent problems with the sense of smell or taste (olfactory/gustatory dysfunction) and two evaluated treatments for neuropsychological sequela.• Two trials were rated positively for 12 out of the 13 quality criteria that we assessed and three met 11 criteria. The remaining 11 trials gained a positive rating for between seven and ten criteria. ",

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