Treatment and rehabilitation of Long COVID: A scope of the literature.: Update April 2023

Gary Austin Raine; Claire Louise Khouja; Meena Khatwa; Melissa Harden; Katy Sutcliffe; Amanda Jayne Sowden

Treatment and rehabilitation of Long COVID: A scope of the literature. Update April 2023

Gary Austin Raine, Claire Louise Khouja, Meena Khatwa, Melissa Harden, Katy Sutcliffe, Amanda Jayne Sowden

Centre for Reviews and Dissemination

Research output: Book/Report › Commissioned report

Abstract

Summary
• We identified 18 randomised controlled trials published since December 2022 that were focused on Long COVID treatment or rehabilitation. Across our four reports produced to date, we have identified and assessed 55 trials published between January 2022 and March 2023.
• A third of the trials included in this update had a primary focus on treating persistent problems with respiratory function and physical fitness (n=6). Other trials focused on olfactory dysfunction (n=5); long-term fatigue (n=2); headaches (n=1) and cognitive impairment, physical and mental fatigue and neuropsychiatric issues (n=1). Three trials evaluated interventions for treating non-specific Long COVID symptoms, all of which were focused on improving physical fitness.
• Five trials were rated positively for at least 11 out of the 13 criteria that we assessed. Four trials met 10 criteria and nine gained a positive rating for between five and nine criteria.

Original language	English
Place of Publication	London
Publisher	EPPI-Centre, Social Science Research Unit, UCL Institute of Education, University College London.
Commissioning body	NIHR Policy Research Programme
Number of pages	26
ISBN (Electronic)	978-1-911605-43-0
Publication status	Published - Apr 2023

Access to Document

LC_treatment4_April23_LO-200623
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Final published version, 580 KBLicence: CC BY-NC

Cite this

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title = "Treatment and rehabilitation of Long COVID: A scope of the literature.: Update April 2023",

abstract = "Summary• We identified 18 randomised controlled trials published since December 2022 that were focused on Long COVID treatment or rehabilitation. Across our four reports produced to date, we have identified and assessed 55 trials published between January 2022 and March 2023.• A third of the trials included in this update had a primary focus on treating persistent problems with respiratory function and physical fitness (n=6). Other trials focused on olfactory dysfunction (n=5); long-term fatigue (n=2); headaches (n=1) and cognitive impairment, physical and mental fatigue and neuropsychiatric issues (n=1). Three trials evaluated interventions for treating non-specific Long COVID symptoms, all of which were focused on improving physical fitness.• Five trials were rated positively for at least 11 out of the 13 criteria that we assessed. Four trials met 10 criteria and nine gained a positive rating for between five and nine criteria.",

author = "Raine, {Gary Austin} and Khouja, {Claire Louise} and Meena Khatwa and Melissa Harden and Katy Sutcliffe and Sowden, {Amanda Jayne}",

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AU - Raine, Gary Austin

AU - Khouja, Claire Louise

AU - Khatwa, Meena

AU - Harden, Melissa

AU - Sutcliffe, Katy

AU - Sowden, Amanda Jayne

PY - 2023/4

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N2 - Summary• We identified 18 randomised controlled trials published since December 2022 that were focused on Long COVID treatment or rehabilitation. Across our four reports produced to date, we have identified and assessed 55 trials published between January 2022 and March 2023.• A third of the trials included in this update had a primary focus on treating persistent problems with respiratory function and physical fitness (n=6). Other trials focused on olfactory dysfunction (n=5); long-term fatigue (n=2); headaches (n=1) and cognitive impairment, physical and mental fatigue and neuropsychiatric issues (n=1). Three trials evaluated interventions for treating non-specific Long COVID symptoms, all of which were focused on improving physical fitness.• Five trials were rated positively for at least 11 out of the 13 criteria that we assessed. Four trials met 10 criteria and nine gained a positive rating for between five and nine criteria.

AB - Summary• We identified 18 randomised controlled trials published since December 2022 that were focused on Long COVID treatment or rehabilitation. Across our four reports produced to date, we have identified and assessed 55 trials published between January 2022 and March 2023.• A third of the trials included in this update had a primary focus on treating persistent problems with respiratory function and physical fitness (n=6). Other trials focused on olfactory dysfunction (n=5); long-term fatigue (n=2); headaches (n=1) and cognitive impairment, physical and mental fatigue and neuropsychiatric issues (n=1). Three trials evaluated interventions for treating non-specific Long COVID symptoms, all of which were focused on improving physical fitness.• Five trials were rated positively for at least 11 out of the 13 criteria that we assessed. Four trials met 10 criteria and nine gained a positive rating for between five and nine criteria.

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