Tributyltin hydride-mediated tandem reactions of dehydroalanines leading to α-substituted pyroglutamates

S. C. Baker; K. Goodall; A. F. Parsons; M. Wilson

doi:10.3184/030823400103167651

Tributyltin hydride-mediated tandem reactions of dehydroalanines leading to α-substituted pyroglutamates

S. C. Baker, K. Goodall, A. F. Parsons^*, M. Wilson

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Tributyltin hydride-mediated cyclisation of dehydroalanines produces an intermediate captodative radical, which can be trapped by reaction with oxygen- or carbon-centred radicals or (principally) electron-poor alkenes, to provide a quick approach to a variety of α-substituted pyroglutamates.

Original language	English
Pages (from-to)	312-313
Number of pages	2
Journal	Journal of Chemical Research - Part S
Issue number	7
DOIs	https://doi.org/10.3184/030823400103167651
Publication status	Published - 2000

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title = "Tributyltin hydride-mediated tandem reactions of dehydroalanines leading to α-substituted pyroglutamates",

abstract = "Tributyltin hydride-mediated cyclisation of dehydroalanines produces an intermediate captodative radical, which can be trapped by reaction with oxygen- or carbon-centred radicals or (principally) electron-poor alkenes, to provide a quick approach to a variety of α-substituted pyroglutamates.",

author = "Baker, {S. C.} and K. Goodall and Parsons, {A. F.} and M. Wilson",

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AU - Parsons, A. F.

AU - Wilson, M.

PY - 2000

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AB - Tributyltin hydride-mediated cyclisation of dehydroalanines produces an intermediate captodative radical, which can be trapped by reaction with oxygen- or carbon-centred radicals or (principally) electron-poor alkenes, to provide a quick approach to a variety of α-substituted pyroglutamates.

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EP - 313

JO - Journal of Chemical Research - Part S

JF - Journal of Chemical Research - Part S

IS - 7

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Tributyltin hydride-mediated tandem reactions of dehydroalanines leading to α-substituted pyroglutamates

Abstract

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