TriTrypDB: a functional genomic resource for the Trypanosomatidae

Martin Aslett, Cristina Aurrecoechea, Matthew Berriman, John Brestelli, Brian P Brunk, Mark Carrington, Daniel P Depledge, Steve Fischer, Bindu Gajria, Xin Gao, Malcolm J Gardner, Alan Gingle, Greg Grant, Omar S Harb, Mark Heiges, Christiane Hertz-Fowler, Robin Houston, Frank Innamorato, John Iodice, Jessica C KissingerEileen Kraemer, Wei Li, Flora J Logan, John A Miller, Siddhartha Mitra, Peter J Myler, Vishal Nayak, Cary Pennington, Isabelle Phan, Deborah F Pinney, Gowthaman Ramasamy, Matthew B Rogers, David S Roos, Chris Ross, Dhileep Sivam, Deborah F Smith, Ganesh Srinivasamoorthy, Christian J Stoeckert, Sandhya Subramanian, Ryan Thibodeau, Adrian Tivey, Charles Treatman, Giles Velarde, Haiming Wang

Research output: Contribution to journalArticlepeer-review


TriTrypDB ( is an integrated database providing access to genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex queries driven by research and development needs. TriTrypDB is a collaborative project, utilizing the GUS/WDK computational infrastructure developed by the Eukaryotic Pathogen Bioinformatics Resource Center ( to integrate genome annotation and analyses from GeneDB and elsewhere with a wide variety of functional genomics datasets made available by members of the global research community, often pre-publication. Currently, TriTrypDB integrates datasets from Leishmania braziliensis, L. infantum, L. major, L. tarentolae, Trypanosoma brucei and T. cruzi. Users may examine individual genes or chromosomal spans in their genomic context, including syntenic alignments with other kinetoplastid organisms. Data within TriTrypDB can be interrogated utilizing a sophisticated search strategy system that enables a user to construct complex queries combining multiple data types. All search strategies are stored, allowing future access and integrated searches. 'User Comments' may be added to any gene page, enhancing available annotation; such comments become immediately searchable via the text search, and are forwarded to curators for incorporation into the reference annotation when appropriate.

Original languageEnglish
Pages (from-to)D457-62
JournalNucleic Acids Research
Issue numberDatabase issue
Publication statusPublished - Jan 2010


  • Animals
  • Computational Biology
  • Databases, Genetic
  • Databases, Nucleic Acid
  • Databases, Protein
  • Genome, Protozoan
  • Information Storage and Retrieval
  • Internet
  • Leishmania
  • Protein Structure, Tertiary
  • Protozoan Proteins
  • Software
  • Trypanosoma
  • User-Computer Interface

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