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Tuning hardness in calcite by incorporation of amino acids

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JournalNature Materials
DateAccepted/In press - 24 Mar 2016
DateE-pub ahead of print - 2 May 2016
DatePublished (current) - 1 Aug 2016
Issue number8
Number of pages8
Pages (from-to)903-910
Early online date2/05/16
Original languageEnglish


Structural biominerals are inorganic/organic composites that exhibit remarkable mechanical properties. However, the structure–property relationships of even the simplest building unit—mineral single crystals containing embedded macromolecules—remain poorly understood. Here, by means of a model biomineral made from calcite single crystals containing glycine (0–7 mol%) or aspartic acid (0–4 mol%), we elucidate the origin of the superior hardness of biogenic calcite. We analysed lattice distortions in these model crystals by using X-ray diffraction and molecular dynamics simulations, and by means of solid-state nuclear magnetic resonance show that the amino acids are incorporated as individual molecules.We also demonstrate that nanoindentation hardness increased with amino acid content, reaching values equivalent to their biogenic counterparts. A dislocation pinning model reveals that the enhanced hardness is determined by the force required to cut covalent bonds in the molecules.

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