Two-stage meta-analysis of survival data from individual participants using percentile ratios

TY - JOUR

T1 - Two-stage meta-analysis of survival data from individual participants using percentile ratios

AU - Barrett, Jessica K

AU - Farewell, Vern T

AU - Siannis, Fotios

AU - Tierney, Jayne

AU - Higgins, Julian P T

N1 - Copyright © 2012 John Wiley & Sons, Ltd.

PY - 2012

Y1 - 2012

N2 - Methods for individual participant data meta-analysis of survival outcomes commonly focus on the hazard ratio as a measure of treatment effect. Recently, Siannis et al. (2010, Statistics in Medicine 29:3030-3045) proposed the use of percentile ratios as an alternative to hazard ratios. We describe a novel two-stage method for the meta-analysis of percentile ratios that avoids distributional assumptions at the study level. Copyright © 2012 John Wiley & Sons, Ltd.

AB - Methods for individual participant data meta-analysis of survival outcomes commonly focus on the hazard ratio as a measure of treatment effect. Recently, Siannis et al. (2010, Statistics in Medicine 29:3030-3045) proposed the use of percentile ratios as an alternative to hazard ratios. We describe a novel two-stage method for the meta-analysis of percentile ratios that avoids distributional assumptions at the study level. Copyright © 2012 John Wiley & Sons, Ltd.

UR - http://www.scopus.com/inward/record.url?scp=84864088299&partnerID=8YFLogxK

U2 - 10.1002/sim.5516

DO - 10.1002/sim.5516

M3 - Article

C2 - 22825835

JO - Statistics in Medicine

JF - Statistics in Medicine

ER -