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Unexpected Preferential Dehydration of Artemisinin in Ionic Liquids
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Publication details
| Journal | Journal of Physical Chemistry A |
|---|---|
| Date | E-pub ahead of print - 1 Sep 2009 |
| Date | Published (current) - 24 Sep 2009 |
| Issue number | 38 |
| Volume | 113 |
| Number of pages | 3 |
| Pages (from-to) | 10143-10145 |
| Early online date | 1/09/09 |
| Original language | English |
Abstract
Thermodynamic measurements (at 298 K) reveal that a crucial step in the extraction process of the key antimalarial drug artemisinin by ionic liquids (ILs), namely, precipitation through the addition of water, is driven by artemisinin dehydration due to the differences in the water's interaction with the bulk ILs, rather than with the artemisinin itself.
- INTERACTION COEFFICIENTS, TEMPERATURE, HYDRATION, ETHANOL
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Protein interactions in ionic media
Project: Research project (funded) › Research
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