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Unexpected Preferential Dehydration of Artemisinin in Ionic Liquids

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JournalJournal of Physical Chemistry A
DateE-pub ahead of print - 1 Sep 2009
DatePublished (current) - 24 Sep 2009
Issue number38
Volume113
Number of pages3
Pages (from-to)10143-10145
Early online date1/09/09
Original languageEnglish

Abstract

Thermodynamic measurements (at 298 K) reveal that a crucial step in the extraction process of the key antimalarial drug artemisinin by ionic liquids (ILs), namely, precipitation through the addition of water, is driven by artemisinin dehydration due to the differences in the water's interaction with the bulk ILs, rather than with the artemisinin itself.

    Research areas

  • INTERACTION COEFFICIENTS, TEMPERATURE, HYDRATION, ETHANOL

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