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From the same journal

United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder: study protocol for a randomised controlled trial

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United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder : study protocol for a randomised controlled trial. / Brealey, Stephen; Armstrong, Alison L; Brooksbank, Andrew; Carr, Andrew Jonathan; Charalambous, Charalambos P; Cooper, Cushla; Corbacho Martín, Belén; Dias, Joseph; Donnelly, Iona; Goodchild, Lorna; Hewitt, Catherine; Keding, Ada; Kottam, Lucksy; Lamb, Sarah E; McDaid, Catriona; Northgraves, Matthew; Richardson, Gerry; Rodgers, Sara; Shah, Sarwat; Sharp, Emma; Spencer, Sally; Torgerson, David; Toye, Francine; Rangan, Amar.

In: Trials, Vol. 18, No. 1, 614, 22.12.2017.

Research output: Contribution to journalArticle

Harvard

Brealey, S, Armstrong, AL, Brooksbank, A, Carr, AJ, Charalambous, CP, Cooper, C, Corbacho Martín, B, Dias, J, Donnelly, I, Goodchild, L, Hewitt, C, Keding, A, Kottam, L, Lamb, SE, McDaid, C, Northgraves, M, Richardson, G, Rodgers, S, Shah, S, Sharp, E, Spencer, S, Torgerson, D, Toye, F & Rangan, A 2017, 'United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder: study protocol for a randomised controlled trial', Trials, vol. 18, no. 1, 614. https://doi.org/10.1186/s13063-017-2352-2

APA

Brealey, S., Armstrong, A. L., Brooksbank, A., Carr, A. J., Charalambous, C. P., Cooper, C., ... Rangan, A. (2017). United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder: study protocol for a randomised controlled trial. Trials, 18(1), [614]. https://doi.org/10.1186/s13063-017-2352-2

Vancouver

Brealey S, Armstrong AL, Brooksbank A, Carr AJ, Charalambous CP, Cooper C et al. United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder: study protocol for a randomised controlled trial. Trials. 2017 Dec 22;18(1). 614. https://doi.org/10.1186/s13063-017-2352-2

Author

Brealey, Stephen ; Armstrong, Alison L ; Brooksbank, Andrew ; Carr, Andrew Jonathan ; Charalambous, Charalambos P ; Cooper, Cushla ; Corbacho Martín, Belén ; Dias, Joseph ; Donnelly, Iona ; Goodchild, Lorna ; Hewitt, Catherine ; Keding, Ada ; Kottam, Lucksy ; Lamb, Sarah E ; McDaid, Catriona ; Northgraves, Matthew ; Richardson, Gerry ; Rodgers, Sara ; Shah, Sarwat ; Sharp, Emma ; Spencer, Sally ; Torgerson, David ; Toye, Francine ; Rangan, Amar. / United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder : study protocol for a randomised controlled trial. In: Trials. 2017 ; Vol. 18, No. 1.

Bibtex - Download

@article{cff3b03c07e4460f9a037f1f8dc75077,
title = "United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder: study protocol for a randomised controlled trial",
abstract = "BACKGROUND: Frozen shoulder (also known as adhesive capsulitis) occurs when the capsule, or the soft tissue envelope around the ball and socket shoulder joint, becomes scarred and contracted, making the shoulder tight, painful and stiff. It affects around 1 in 12 men and 1 in 10 women of working age. Although this condition can settle with time (typically taking 1 to 3 years), for some people it causes severe symptoms and needs referral to hospital. Our aim is to evaluate the clinical and cost-effectiveness of two invasive and costly surgical interventions that are commonly used in secondary care in the National Health Service (NHS) compared with a non-surgical comparator of Early Structured Physiotherapy.METHODS: We will conduct a randomised controlled trial (RCT) of 500 adult patients with a clinical diagnosis of frozen shoulder, and who have radiographs that exclude other pathology. Early Structured Physiotherapy with an intra-articular steroid injection will be compared with manipulation under anaesthesia with a steroid injection or arthroscopic (keyhole) capsular release followed by manipulation. Both surgical interventions will be followed with a programme of post-procedural physiotherapy. These treatments will be undertaken in NHS hospitals across the United Kingdom. The primary outcome and endpoint will be the Oxford Shoulder Score (a patient self-reported assessment of shoulder function) at 12 months. This will also be measured at baseline, 3 and 6 months after randomisation; and on the day that treatment starts and 6 months later. Secondary outcomes include the Disabilities of Arm Shoulder and Hand (QuickDASH) score, the EQ-5D-5 L score, pain, extent of recovery and complications. We will explore the acceptability of the different treatments to patients and health care professionals using qualitative methods.DISCUSSION: The three treatments being compared are the most frequently used in secondary care in the NHS, but there is uncertainty about which one works best and at what cost. UK FROST is a rigorously designed and adequately powered study to inform clinical decisions for the treatment of this common condition in adults.TRIAL REGISTRATION: International Standard Randomised Controlled Trial Register, ID: ISRCTN48804508 . Registered on 25 July 2014.",
keywords = "Journal Article",
author = "Stephen Brealey and Armstrong, {Alison L} and Andrew Brooksbank and Carr, {Andrew Jonathan} and Charalambous, {Charalambos P} and Cushla Cooper and {Corbacho Mart{\'i}n}, Bel{\'e}n and Joseph Dias and Iona Donnelly and Lorna Goodchild and Catherine Hewitt and Ada Keding and Lucksy Kottam and Lamb, {Sarah E} and Catriona McDaid and Matthew Northgraves and Gerry Richardson and Sara Rodgers and Sarwat Shah and Emma Sharp and Sally Spencer and David Torgerson and Francine Toye and Amar Rangan",
note = "{\circledC} The Author(s). 2017.",
year = "2017",
month = "12",
day = "22",
doi = "10.1186/s13063-017-2352-2",
language = "English",
volume = "18",
journal = "Trials",
issn = "1745-6215",
publisher = "BioMed Central",
number = "1",

}

RIS (suitable for import to EndNote) - Download

TY - JOUR

T1 - United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder

T2 - study protocol for a randomised controlled trial

AU - Brealey, Stephen

AU - Armstrong, Alison L

AU - Brooksbank, Andrew

AU - Carr, Andrew Jonathan

AU - Charalambous, Charalambos P

AU - Cooper, Cushla

AU - Corbacho Martín, Belén

AU - Dias, Joseph

AU - Donnelly, Iona

AU - Goodchild, Lorna

AU - Hewitt, Catherine

AU - Keding, Ada

AU - Kottam, Lucksy

AU - Lamb, Sarah E

AU - McDaid, Catriona

AU - Northgraves, Matthew

AU - Richardson, Gerry

AU - Rodgers, Sara

AU - Shah, Sarwat

AU - Sharp, Emma

AU - Spencer, Sally

AU - Torgerson, David

AU - Toye, Francine

AU - Rangan, Amar

N1 - © The Author(s). 2017.

PY - 2017/12/22

Y1 - 2017/12/22

N2 - BACKGROUND: Frozen shoulder (also known as adhesive capsulitis) occurs when the capsule, or the soft tissue envelope around the ball and socket shoulder joint, becomes scarred and contracted, making the shoulder tight, painful and stiff. It affects around 1 in 12 men and 1 in 10 women of working age. Although this condition can settle with time (typically taking 1 to 3 years), for some people it causes severe symptoms and needs referral to hospital. Our aim is to evaluate the clinical and cost-effectiveness of two invasive and costly surgical interventions that are commonly used in secondary care in the National Health Service (NHS) compared with a non-surgical comparator of Early Structured Physiotherapy.METHODS: We will conduct a randomised controlled trial (RCT) of 500 adult patients with a clinical diagnosis of frozen shoulder, and who have radiographs that exclude other pathology. Early Structured Physiotherapy with an intra-articular steroid injection will be compared with manipulation under anaesthesia with a steroid injection or arthroscopic (keyhole) capsular release followed by manipulation. Both surgical interventions will be followed with a programme of post-procedural physiotherapy. These treatments will be undertaken in NHS hospitals across the United Kingdom. The primary outcome and endpoint will be the Oxford Shoulder Score (a patient self-reported assessment of shoulder function) at 12 months. This will also be measured at baseline, 3 and 6 months after randomisation; and on the day that treatment starts and 6 months later. Secondary outcomes include the Disabilities of Arm Shoulder and Hand (QuickDASH) score, the EQ-5D-5 L score, pain, extent of recovery and complications. We will explore the acceptability of the different treatments to patients and health care professionals using qualitative methods.DISCUSSION: The three treatments being compared are the most frequently used in secondary care in the NHS, but there is uncertainty about which one works best and at what cost. UK FROST is a rigorously designed and adequately powered study to inform clinical decisions for the treatment of this common condition in adults.TRIAL REGISTRATION: International Standard Randomised Controlled Trial Register, ID: ISRCTN48804508 . Registered on 25 July 2014.

AB - BACKGROUND: Frozen shoulder (also known as adhesive capsulitis) occurs when the capsule, or the soft tissue envelope around the ball and socket shoulder joint, becomes scarred and contracted, making the shoulder tight, painful and stiff. It affects around 1 in 12 men and 1 in 10 women of working age. Although this condition can settle with time (typically taking 1 to 3 years), for some people it causes severe symptoms and needs referral to hospital. Our aim is to evaluate the clinical and cost-effectiveness of two invasive and costly surgical interventions that are commonly used in secondary care in the National Health Service (NHS) compared with a non-surgical comparator of Early Structured Physiotherapy.METHODS: We will conduct a randomised controlled trial (RCT) of 500 adult patients with a clinical diagnosis of frozen shoulder, and who have radiographs that exclude other pathology. Early Structured Physiotherapy with an intra-articular steroid injection will be compared with manipulation under anaesthesia with a steroid injection or arthroscopic (keyhole) capsular release followed by manipulation. Both surgical interventions will be followed with a programme of post-procedural physiotherapy. These treatments will be undertaken in NHS hospitals across the United Kingdom. The primary outcome and endpoint will be the Oxford Shoulder Score (a patient self-reported assessment of shoulder function) at 12 months. This will also be measured at baseline, 3 and 6 months after randomisation; and on the day that treatment starts and 6 months later. Secondary outcomes include the Disabilities of Arm Shoulder and Hand (QuickDASH) score, the EQ-5D-5 L score, pain, extent of recovery and complications. We will explore the acceptability of the different treatments to patients and health care professionals using qualitative methods.DISCUSSION: The three treatments being compared are the most frequently used in secondary care in the NHS, but there is uncertainty about which one works best and at what cost. UK FROST is a rigorously designed and adequately powered study to inform clinical decisions for the treatment of this common condition in adults.TRIAL REGISTRATION: International Standard Randomised Controlled Trial Register, ID: ISRCTN48804508 . Registered on 25 July 2014.

KW - Journal Article

U2 - 10.1186/s13063-017-2352-2

DO - 10.1186/s13063-017-2352-2

M3 - Article

VL - 18

JO - Trials

JF - Trials

SN - 1745-6215

IS - 1

M1 - 614

ER -