By the same authors

From the same journal

From the same journal

Unprecedented meta-substitution of calixarenes: Direct way to inherently chiral derivatives

Research output: Contribution to journalArticlepeer-review

Published copy (DOI)


  • Petr Slavik
  • Miroslav Dudic
  • Karolina Flidrova
  • Jan Sykora
  • Ivana Cisarova
  • Stanislav Böhm
  • Pavel Lhotak


Publication details

JournalOrganic Letters
DatePublished - 20 Jul 2012
Issue number14
Number of pages4
Pages (from-to)3628-3631
Original languageEnglish


Electrophilic aromatic substitution in the calix[n]arene series is a well-established procedure leading exclusively to para-substituted derivatives. An unprecedented regioselectivity of the mercuration reaction leading to the meta-substituted calix[4]arenes is described. These compounds represent a new type of substitution pattern in classical calixarene chemistry and open the door for the straightforward synthesis of inherently chiral receptors based on calixarenes.

Discover related content

Find related publications, people, projects, datasets and more using interactive charts.

View graph of relations