Use of donor bladder tissues for in vitro research

Mary Garthwaite, Jennifer Hinley, William Cross, Ruth M Warwick, Anita Ambrose, Henry Hardaker, Ian Eardley, Jennifer Southgate

Research output: Contribution to journalArticlepeer-review


To evaluate deceased non-heart beating (DNHB) donors and deceased heart beating (DHB) brain-stem dead donors, as sources of viable urological tissue for use in biomedical research. To identify sources of viable human bladder tissue as an essential resource for cell biological research aimed at understanding human diseases of the bladder and for developing new tissue engineering and regenerative medicine strategies for bladder reconstruction. Typically, normal human urinary tract tissue is obtained from adult or paediatric surgical patients with benign urological conditions, but few surgical procedures yield useful quantities of healthy bladder tissue for research.
Original languageEnglish
Pages (from-to)160-166
Number of pages7
JournalBJU International
Issue number1
Publication statusPublished - Jan 2014

Bibliographical note

© 2013 The Authors. BJU International © 2013 BJU International.


  • Biomedical Research
  • Cell Culture Techniques
  • Cell Proliferation
  • Cells, Cultured
  • Female
  • Humans
  • Immunohistochemistry
  • Male
  • Tissue Donors
  • Urinary Bladder
  • Urothelium

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