Utilisation of water soluble iridium catalysts for signal amplification by reversible exchange

TY - JOUR

T1 - Utilisation of water soluble iridium catalysts for signal amplification by reversible exchange

AU - Fekete, M

AU - Gibard, C

AU - Dear, G J

AU - Green, G G R

AU - Hooper, A J J

AU - Roberts, A D

AU - Cisnetti, F

AU - Duckett, S B

N1 - © The Royal Society of Chemistry 2015.

PY - 2015/4/21

Y1 - 2015/4/21

N2 - The catalytic hyperpolarisation of pyridine, 3-hydroxypyridine and oxazole by the Signal Amplification By Reversible Exchange (SABRE) process is achieved by a series of water soluble iridium phosphine and N-heterocyclic carbene dihydride complexes. While the efficiency of the SABRE process in methanol-d4 solution or ethanol-d6 solution is high, with over 400-fold (1)H polarisation of pyridine being produced by [Ir(H)2(NCMe)(py)(IMes)(monosulfonated-triphenylphosphine)]BF4, changing to a D2O or a D2O-ethanol solvent mixture leads to dramatically reduced activity which is rationalised in terms of low H2 solubility.

AB - The catalytic hyperpolarisation of pyridine, 3-hydroxypyridine and oxazole by the Signal Amplification By Reversible Exchange (SABRE) process is achieved by a series of water soluble iridium phosphine and N-heterocyclic carbene dihydride complexes. While the efficiency of the SABRE process in methanol-d4 solution or ethanol-d6 solution is high, with over 400-fold (1)H polarisation of pyridine being produced by [Ir(H)2(NCMe)(py)(IMes)(monosulfonated-triphenylphosphine)]BF4, changing to a D2O or a D2O-ethanol solvent mixture leads to dramatically reduced activity which is rationalised in terms of low H2 solubility.

U2 - 10.1039/c5dt00311c

DO - 10.1039/c5dt00311c

M3 - Article

C2 - 25823378

SN - 1477-9234

VL - 44

SP - 7870

EP - 7880

JO - Dalton Transactions

JF - Dalton Transactions

IS - 17

ER -