Validation tools: can they indicate the information content of macromolecular crystal structures?

TY - JOUR

T1 - Validation tools: can they indicate the information content of macromolecular crystal structures?

AU - Dodson, E J

AU - Davies, G J

AU - Lamzin, V S

AU - Murshudov, G N

AU - Wilson, K S

PY - 1998/6/15

Y1 - 1998/6/15

N2 - The explosive increase in the number of published three-dimensional structures of macromolecules determined by X-ray analysis places a responsibility on experimentalists, referees and curators of databases to ensure correspondence between the structure parameters and data. Validation tools will evolve as more appropriate statistical techniques and new information, such as that from proteins analysed at atomic resolution, becomes available.

AB - The explosive increase in the number of published three-dimensional structures of macromolecules determined by X-ray analysis places a responsibility on experimentalists, referees and curators of databases to ensure correspondence between the structure parameters and data. Validation tools will evolve as more appropriate statistical techniques and new information, such as that from proteins analysed at atomic resolution, becomes available.

KW - STRUCTURE REFINEMENT

KW - PROTEIN

KW - DYNAMICS

KW - DISPLAY

KW - PROGRAM

M3 - Article

SN - 0969-2126

VL - 6

SP - 685

EP - 690

JO - Structure

JF - Structure

IS - 6

ER -