Paul Genever

Contact details

Type of addressPostal address
Postal codeYO10 5DD
CountryUnited Kingdom
Address lines
  • Biology
    University of York
    Wentworth Way
    York
    YO10 5DD

Phone: (01904) 328649

No renderer: orcidPortalIcon,dk.atira.pure.api.shared.model.person.Person

Discover related content

Find related publications, people, projects, datasets and more using interactive charts.

View graph of relations

Prof. Paul Genever

Professor

Areas of expertise

  • Stem cells and regenerative medicine
  • Bone marrow stromal cells
  • Bone biology and disorders of the skeleton
  • Biomedical research, cell & molecular biology

PhD opportunities

Analysis of mesenchymal stromal/stem cell sub-populations

Human mesenchymal stromal/stem cells (MSCs) are found in adult tissues such as bone marrow and are able to differentiate into osteogenic, chondrogenic and adipogenic tissues. There is intense interest in determining how MSCs may be used in future cell-based therapies, including gene therapy, immunotherapy and tissue engineering, and as in vitro models for fundamental research and drug discovery. However, little is known about MSC identity and research is often performed on heterogeneous mixtures of different MSC sub-populations. Using a process of telomerase-based immortalisation and cell cloning, we have generated several different MSC lines that represent different “types” of MSCs. For example, some MSC lines demonstrate tri-lineage, whereas other are bi-potent, uni-potent or nulli-potent. This project will examine the differentiation characteristics of these MSC lines to determine how they reflect MSC sub-populations in vivo. Self-funded.
  • Festival of Ideas 2018

    Activity: Participating in or organising an eventOutreach (e.g. schools, community groups)

View all (1) »